Human Recombinant PTN (from E. coli)

About this item

Pleiotrophin (PTN) is a heparin-binding growth factor that has mitogenic effects on fibroblast, epithelial, and endothelial cells. PTN is made by many tissues, but is predominantly secreted by nervous tissue during development. PTN induces neurite outgrowth and is involved in tumor growth and metastasis.

High quality
Low endotoxin
Affordable

PTN binds with low affinity to the cell surface receptor nucleolin to inhibit HIV-1 infection. PNT also binds the receptor protein tyrosine phosphatase type Z (PTPRZ), syndecan-3, and anaplastic lymphoma kinase (ALK) receptors.

It is also binds the receptor protein tyrosine phosphatase type Z (PTPRZ), syndecan-3, and anaplastic lymphoma kinase (ALK) receptors.

Delivery: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.

Caution: For research use only.

Specifications

Coniugazione:
Non coniugato
Protein function:
Cytokine
Protein/peptide type:
Recombinant
Sorgente luminosa:
E. coli
Specie:
Human
Condizioni di conservazione:
−20 °C
Contenuto di endotossine:
Endotoxin LAL (EU/µg) ≤0.1
Attività biologica:
Bioactivity: No biological activity data is available at this time
ID gene:
P21246
Ricostituzione:
Sterile water at 0,1 mg/ml
Privo di endotossine:
N
Senza corriere:
Y
Protease-free:
N
Senza animali:
N
Protein synonyms:
NEGF1|HARP|HBBM|HBGF-8
UniProtKB:
P21246
Protein/peptide name:
Pleiotrophin
Purezza:
≥95%
Peso molecolare:
15,4 kDa
Sequenza:
MGKKEKPEKK VKKSDCGEWQ WSVCVPTSGD CGLGTREGTR TGAECKQTMK TQRCKIPCNW KKQFGAECKY QFQAWGECDL NTALKTRTGS LKRALHNAEC QKTVTISKPC GKLTKPKPQA ESKKKKKEGK KQEKMLD
Livello di endotossine:
Low
Formulazione:
10 mM sodium phosphate, pH 7,5
Esente da nucleasi:
N
Grado:
RUO
Temperatura di spedizione:
RT