Human Recombinant G-CSF (from E. coli)
Informazioni su questo articolo
Granulocyte-colony stimulating factor (G-CSF) is a cytokine that functions as a potent inducer of neutrophilic granulocyte proliferation, terminal differentiation, and activation. G-CSF synthesis occurs in monocyte, macrophage, epithelial, endothelial, and fibroblast cells after activation by bacterial endotoxins, tumor necrosis factor alpha (TNF-α), interleukin 1 (IL-1), or interleukin 17 (IL-17).
- High quality
- Low endotoxin
- Affordable
The functional activity of G-CSF is mediated through the granulocyte colony-stimulating factor receptor (G-CSF-R) to activate JAK/STAT and MAPK signal transduction pathways. G-CSF also promotes neurogenesis and inhibits neuronal apoptosis. Human and mouse G-CSF proteins are cross-reactive.
The functional activity of G-CSF is mediated through the granulocyte colony-stimulating factor receptor (G-CSF-R) to activate JAK/STAT and MAPK signal transduction pathways. G-CSF also promotes neurogenesis and inhibits neuronal apoptosis. Human and mouse G-CSF proteins are cross-reactive.
Lieferinformationen: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
Achtung! Bitte beachten: For research use only.
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Product Details & Documents
Granulocyte-colony stimulating factor (G-CSF) is a cytokine that functions as a potent inducer of neutrophilic granulocyte proliferation, terminal differentiation, and activation. G-CSF synthesis occurs in monocyte, macrophage, epithelial, endothelial, and fibroblast cells after activation by bacterial endotoxins, tumor necrosis factor alpha (TNF-α), interleukin 1 (IL-1), or interleukin 17 (IL-17).
- High quality
- Low endotoxin
- Affordable
The functional activity of G-CSF is mediated through the granulocyte colony-stimulating factor receptor (G-CSF-R) to activate JAK/STAT and MAPK signal transduction pathways. G-CSF also promotes neurogenesis and inhibits neuronal apoptosis. Human and mouse G-CSF proteins are cross-reactive.
The functional activity of G-CSF is mediated through the granulocyte colony-stimulating factor receptor (G-CSF-R) to activate JAK/STAT and MAPK signal transduction pathways. G-CSF also promotes neurogenesis and inhibits neuronal apoptosis. Human and mouse G-CSF proteins are cross-reactive.
Lieferinformationen: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
Achtung! Bitte beachten: For research use only.
Specifications for Product Family
Specifiche
Specifiche
- Catalog No:
- SHBT100-72-10UG
- SHBT100-72-100UG
- SHBT100-72-1MG
- Protein/peptide name:
- G-CSF
- G-CSF
- G-CSF
- Protein synonyms:
- GM-CSFβ|pluripoietin|MGI-1G|CSF-3
- GM-CSFβ|pluripoietin|MGI-1G|CSF-3
- GM-CSFβ|pluripoietin|MGI-1G|CSF-3
- Protein/peptide type:
- Recombinant
- Recombinant
- Recombinant
- Protein function:
- Cytokine
- Cytokine
- Cytokine
- Specie:
- Human
- Human
- Human
- Sorgente luminosa:
- E. coli
- E. coli
- E. coli
- Coniugazione:
- Non coniugato
- Non coniugato
- Non coniugato
- ID gene:
- P09919
- P09919
- P09919
- Sequenza:
- MTPLGPASSL PQSFLLKCLE QVRKIQGDGA ALQEKLCATY KLCHPEELVL LGHSLGIPWA PLSSCPSQAL QLAGCLSQLH SGLFLYQGLL QALEGISPEL GPTLDTLQLD VADFATTIWQ QMEELGMAPA LQPTQGAMPA FASAFQRRAG GVLVASHLQS FLEVSYRVLR HLAQP
- MTPLGPASSL PQSFLLKCLE QVRKIQGDGA ALQEKLCATY KLCHPEELVL LGHSLGIPWA PLSSCPSQAL QLAGCLSQLH SGLFLYQGLL QALEGISPEL GPTLDTLQLD VADFATTIWQ QMEELGMAPA LQPTQGAMPA FASAFQRRAG GVLVASHLQS FLEVSYRVLR HLAQP
- MTPLGPASSL PQSFLLKCLE QVRKIQGDGA ALQEKLCATY KLCHPEELVL LGHSLGIPWA PLSSCPSQAL QLAGCLSQLH SGLFLYQGLL QALEGISPEL GPTLDTLQLD VADFATTIWQ QMEELGMAPA LQPTQGAMPA FASAFQRRAG GVLVASHLQS FLEVSYRVLR HLAQP
- Protease-free:
- N
- N
- N
- Senza animali:
- N
- N
- N
- Esente da nucleasi:
- N
- N
- N
- Senza corriere:
- Y
- Y
- Y
- Privo di endotossine:
- N
- N
- N
- Livello di endotossine:
- Low
- Low
- Low
- Contenuto di endotossine:
- Endotoxin LAL (EU/µg) ≤0.1
- Endotoxin LAL (EU/µg) ≤0.1
- Endotoxin LAL (EU/µg) ≤0.1
- UniProtKB:
- P09919
- P09919
- P09919
- Attività biologica:
- Bioactivity assay: NFS-60 cell proliferation, ED50 ≤0,060 ng/ml, bioactivity ≥1,7×10⁷ units/mg
- Bioactivity assay: NFS-60 cell proliferation, ED50 ≤0,060 ng/ml, bioactivity ≥1,7×10⁷ units/mg
- Bioactivity assay: NFS-60 cell proliferation, ED50 ≤0,060 ng/ml, bioactivity ≥1,7×10⁷ units/mg
- Purezza:
- ≥95%
- ≥95%
- ≥95%
- Grado:
- RUO
- RUO
- RUO
- Formulazione:
- 20 mM acetic acid, 50 mM sodium chloride
- 20 mM acetic acid, 50 mM sodium chloride
- 20 mM acetic acid, 50 mM sodium chloride
- Peso molecolare:
- 18,8 kDa
- 18,8 kDa
- 18,8 kDa
- Ricostituzione:
- Sterile water at 0,1 mg/ml
- Sterile water at 0,1 mg/ml
- Sterile water at 0,1 mg/ml
- Condizioni di conservazione:
- −20 °C
- −20 °C
- −20 °C
- Temperatura di spedizione:
- RT
- RT
- RT
- Applicazioni testate:
- Bioassay
- Bioassay
- Bioassay
Specifiche
Product Family Options
Informazioni sul prodotto
- Tipo di conf.ConfDisponibilitàPrice
- Specifiche:
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Specifications
Cat. No.SHBT100-72-10UGProtein/peptide nameG-CSFProtein synonymsGM-CSFβ|pluripoietin|MGI-1G|CSF-3Protein/peptide typeRecombinantProtein functionCytokineSpecieHumanSorgente luminosaE. coliConiugazioneNon coniugatoID geneP09919SequenzaMTPLGPASSL PQSFLLKCLE QVRKIQGDGA ALQEKLCATY KLCHPEELVL LGHSLGIPWA PLSSCPSQAL QLAGCLSQLH SGLFLYQGLL QALEGISPEL GPTLDTLQLD VADFATTIWQ QMEELGMAPA LQPTQGAMPA FASAFQRRAG GVLVASHLQS FLEVSYRVLR HLAQPProtease-freeNSenza animaliNEsente da nucleasiNSenza corriereYPrivo di endotossineNLivello di endotossineLowContenuto di endotossineEndotoxin LAL (EU/µg) ≤0.1UniProtKBP09919Attività biologicaBioactivity assay: NFS-60 cell proliferation, ED50 ≤0,060 ng/ml, bioactivity ≥1,7×10⁷ units/mgPurezza≥95%GradoRUOFormulazione20 mM acetic acid, 50 mM sodium chloridePeso molecolare18,8 kDaRicostituzioneSterile water at 0,1 mg/mlCondizioni di conservazione−20 °CTemperatura di spedizioneRTApplicazioni testateBioassay - Specifiche:
More
Specifications
Cat. No.SHBT100-72-100UGProtein/peptide nameG-CSFProtein synonymsGM-CSFβ|pluripoietin|MGI-1G|CSF-3Protein/peptide typeRecombinantProtein functionCytokineSpecieHumanSorgente luminosaE. coliConiugazioneNon coniugatoID geneP09919SequenzaMTPLGPASSL PQSFLLKCLE QVRKIQGDGA ALQEKLCATY KLCHPEELVL LGHSLGIPWA PLSSCPSQAL QLAGCLSQLH SGLFLYQGLL QALEGISPEL GPTLDTLQLD VADFATTIWQ QMEELGMAPA LQPTQGAMPA FASAFQRRAG GVLVASHLQS FLEVSYRVLR HLAQPProtease-freeNSenza animaliNEsente da nucleasiNSenza corriereYPrivo di endotossineNLivello di endotossineLowContenuto di endotossineEndotoxin LAL (EU/µg) ≤0.1UniProtKBP09919Attività biologicaBioactivity assay: NFS-60 cell proliferation, ED50 ≤0,060 ng/ml, bioactivity ≥1,7×10⁷ units/mgPurezza≥95%GradoRUOFormulazione20 mM acetic acid, 50 mM sodium chloridePeso molecolare18,8 kDaRicostituzioneSterile water at 0,1 mg/mlCondizioni di conservazione−20 °CTemperatura di spedizioneRTApplicazioni testateBioassay - Specifiche:
More
Specifications
Cat. No.SHBT100-72-1MGProtein/peptide nameG-CSFProtein synonymsGM-CSFβ|pluripoietin|MGI-1G|CSF-3Protein/peptide typeRecombinantProtein functionCytokineSpecieHumanSorgente luminosaE. coliConiugazioneNon coniugatoID geneP09919SequenzaMTPLGPASSL PQSFLLKCLE QVRKIQGDGA ALQEKLCATY KLCHPEELVL LGHSLGIPWA PLSSCPSQAL QLAGCLSQLH SGLFLYQGLL QALEGISPEL GPTLDTLQLD VADFATTIWQ QMEELGMAPA LQPTQGAMPA FASAFQRRAG GVLVASHLQS FLEVSYRVLR HLAQPProtease-freeNSenza animaliNEsente da nucleasiNSenza corriereYPrivo di endotossineNLivello di endotossineLowContenuto di endotossineEndotoxin LAL (EU/µg) ≤0.1UniProtKBP09919Attività biologicaBioactivity assay: NFS-60 cell proliferation, ED50 ≤0,060 ng/ml, bioactivity ≥1,7×10⁷ units/mgPurezza≥95%GradoRUOFormulazione20 mM acetic acid, 50 mM sodium chloridePeso molecolare18,8 kDaRicostituzioneSterile water at 0,1 mg/mlCondizioni di conservazione−20 °CTemperatura di spedizioneRTApplicazioni testateBioassay
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