Rat Recombinant IL-17AF (from E. coli)

Über diesen Artikel

Interleukin 17AF (IL-17AF) is a heterodimer that is composed of the interleukin 17A (IL-17A) and interleukin 17F (IL-17F) members of the IL-17 family of cytokines. IL-17AF is produced by T helper 17 cells (Th17) following interleukin 23 (IL-23) stimulation. IL-17AF signals through the IL-17RA/IL-17RC receptor complex and functions to regulate inflammatory responses. IL-17AF induces chemokine and airway neutrophilia production, similar in function to IL-17A and IL-17F homodimers. In regard to these functions, IL-17AF is less active than the IL-17A homodimer and shows greater activity than the IL-17F homodimer. Human and rat IL-17AF are active on mouse cells.

High Quality
Low Endotoxin
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A COA is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions. This product is for research use only and is not for use in humans.

These research grade recombinant proteins are typically used as cytokines, growth factors and chemokines in cell based assays and cell culture.

Caution: For research use only.

Technische Daten

Coniugazione:
Non coniugato
Protein function:
Cytokine
Protein/peptide type:
Recombinant
Sorgente luminosa:
E. coli
Specie:
Rat
Condizioni di conservazione:
–20 °C
Contenuto di endotossine:
Endotoxin LAL (EU/µg) ≤1
Attività biologica:
Bioactivity: No biological activity data is available at this time
ID gene:
Q61453/Q5BJ95
Ricostituzione:
Sterile water at 0.1 mg/ml
Privo di endotossine:
N
Senza corriere:
Y
Protease-free:
N
Senza animali:
N
Protein/peptide name:
IL-17AF
Purezza:
≥95%
Peso molecolare:
30,2 kDa
Sequenza:
IL-17A: MAVLIPQSSV CPNAEANNFL QNVKVNLKVL NSLSSKASSR RPSDYLNRST SPWTLSRNED PDRYPSVIWE AQCRHQRCVN AEGKLDHHMN SVLIQQEILV LKREPEKCPF TFRVEKMLVG VGCTCVSSIV RHAS IL-17F:MARRNPKVGL SALQKAGNCP PLEDNSVRVD IRIFNQNQGI SVPRDFQNRS SSPWD YNITR DPDRFPSEIA EAQCRHSGCI NAQGQEDGSM NSVPIQQEIL VLRREPQGCS NSFRLEKMLI KVGCTCVTPI VHHAA
Livello di endotossine:
Low
Formulazione:
0,1% Trifluoroacetic Acid (TFA)
Esente da nucleasi:
N
Grado:
RUO
Temperatura di spedizione:
RT