Human Recombinant IL-17A (from E. coli)

Human Recombinant IL-17A (from <i>E. coli</i>)

Interleukin 21 (IL-21) is a member of the common-gamma chain family of cytokines that are involved in immunoregulation. IL-21 is normally expressed by activated CD4+ T cells and is aberrantly expressed in Hodgkin lymphoma cells. The IL-21 receptor (IL-21R) activates the JAK/STAT signaling pathway and is expressed on T, B, and natural killer (NK) cells.

High quality
Low endotoxin
Affordable

Within the B cell lineage, IL-21 is a switch factor regulating IgG1 and IgG3 antibody production. IL-21 also cooperates with IL-4 for the production of multiple antibody classes in B cells. IL-21 has pleiotropic effects on the proliferation, differentiation, and effector functions of B, T, NK, and dendritic cells.

Elevated levels of IL-17A are associated with rheumatoid arthritis, airway inflammation, allograft rejection, inflammatory bowel disease, psoriasis, cancer, and multiple sclerosis. Human, mouse, and rat IL-17A show activity on mouse cells.

Delivery information: Certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.

Caution: For research use only.

High quality
Low endotoxin
Affordable

Caution: For research use only.

Catalog No:
SHBT100-87-5UG
SHBT100-87-25UG
SHBT100-87-100UG
SHBT100-87-500UG
SHBT100-87-1MG

Protein/peptide name:
IL-17A
IL-17A
IL-17A
IL-17A
IL-17A

Protein synonyms:
IL-17|CTLA-8
IL-17|CTLA-8
IL-17|CTLA-8
IL-17|CTLA-8
IL-17|CTLA-8

Protein/peptide type:
Recombinant
Recombinant
Recombinant
Recombinant
Recombinant

Protein function:
Cytokine
Cytokine
Cytokine
Cytokine
Cytokine

Specie:
Human
Human
Human
Human
Human

Sorgente luminosa:
E. coli
E. coli
E. coli
E. coli
E. coli

Coniugazione:
Non coniugato
Non coniugato
Non coniugato
Non coniugato
Non coniugato

ID gene:
Q16552
Q16552
Q16552
Q16552
Q16552

Sequenza:
MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA
MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA
MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA
MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA
MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA

Protease-free:
N
N
N
N
N

Senza animali:
N
N
N
N
N

Esente da nucleasi:
N
N
N
N
N

Senza corriere:
Y
Y
Y
Y
Y

Privo di endotossine:
N
N
N
N
N

Livello di endotossine:
Low
Low
Low
Low
Low

Contenuto di endotossine:
Endotoxin LAL (EU/µg) ≤0.1
Endotoxin LAL (EU/µg) ≤0.1
Endotoxin LAL (EU/µg) ≤0.1
Endotoxin LAL (EU/µg) ≤0.1
Endotoxin LAL (EU/µg) ≤0.1

UniProtKB:
Q16552
Q16552
Q16552
Q16552
Q16552

Attività biologica:
Bioactivity assay: Production of IL-6 from mouse 3T3 cells, ED50 ≤10 ng/ml, bioactivity ≥1,0×10⁵ units/mg
Bioactivity assay: Production of IL-6 from mouse 3T3 cells, ED50 ≤10 ng/ml, bioactivity ≥1,0×10⁵ units/mg
Bioactivity assay: Production of IL-6 from mouse 3T3 cells, ED50 ≤10 ng/ml, bioactivity ≥1,0×10⁵ units/mg
Bioactivity assay: Production of IL-6 from mouse 3T3 cells, ED50 ≤10 ng/ml, bioactivity ≥1,0×10⁵ units/mg
Bioactivity assay: Production of IL-6 from mouse 3T3 cells, ED50 ≤10 ng/ml, bioactivity ≥1,0×10⁵ units/mg

Purezza:
≥95%
≥95%
≥95%
≥95%
≥95%

Grado:
RUO
RUO
RUO
RUO
RUO

Formulazione:
0,1% Trifluoroacetic Acid (TFA)
0,1% Trifluoroacetic Acid (TFA)
0,1% Trifluoroacetic Acid (TFA)
0,1% Trifluoroacetic Acid (TFA)
0,1% Trifluoroacetic Acid (TFA)

Peso molecolare:
15,7/31,3 kDa
15,7/31,3 kDa
15,7/31,3 kDa
15,7/31,3 kDa
15,7/31,3 kDa

Ricostituzione:
Sterile water at 0,1 mg/ml
Sterile water at 0,1 mg/ml
Sterile water at 0,1 mg/ml
Sterile water at 0,1 mg/ml
Sterile water at 0,1 mg/ml

Condizioni di conservazione:
−20 °C
−20 °C
−20 °C
−20 °C
−20 °C

Temperatura di spedizione:
RT
RT
RT
RT
RT

Applicazioni testate:
Bioassay
Bioassay
Bioassay
Bioassay
Bioassay

Product Family Options

Tipo di conf.
Conf
SHBT100-87-5UG
Vial
5 µG

1 * 5 µG
1 * 5 µG - SFr. 73.00
SFr. 73.00
1 * 5 µG
SFr. 73.00

Specifications
Cat. No.
SHBT100-87-5UG
Protein/peptide name
IL-17A
Protein synonyms
IL-17|CTLA-8
Protein/peptide type
Recombinant
Protein function
Cytokine
Specie
Human
Sorgente luminosa
E. coli
Coniugazione
Non coniugato
ID gene
Q16552
Sequenza
MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA
Protease-free
N
Senza animali
N
Esente da nucleasi
N
Senza corriere
Y
Privo di endotossine
N
Livello di endotossine
Low
Contenuto di endotossine
Endotoxin LAL (EU/µg) ≤0.1
UniProtKB
Q16552
Attività biologica
Bioactivity assay: Production of IL-6 from mouse 3T3 cells, ED50 ≤10 ng/ml, bioactivity ≥1,0×10⁵ units/mg
Purezza
≥95%
Grado
RUO
Formulazione
0,1% Trifluoroacetic Acid (TFA)
Peso molecolare
15,7/31,3 kDa
Ricostituzione
Sterile water at 0,1 mg/ml
Condizioni di conservazione
−20 °C
Temperatura di spedizione
RT
Applicazioni testate
Bioassay
SHBT100-87-25UG
Vial
25 µG

1 * 25 µG
1 * 25 µG - SFr. 182.00
SFr. 182.00
1 * 25 µG
SFr. 182.00

Specifications
Cat. No.
SHBT100-87-25UG
Protein/peptide name
IL-17A
Protein synonyms
IL-17|CTLA-8
Protein/peptide type
Recombinant
Protein function
Cytokine
Specie
Human
Sorgente luminosa
E. coli
Coniugazione
Non coniugato
ID gene
Q16552
Sequenza
MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA
Protease-free
N
Senza animali
N
Esente da nucleasi
N
Senza corriere
Y
Privo di endotossine
N
Livello di endotossine
Low
Contenuto di endotossine
Endotoxin LAL (EU/µg) ≤0.1
UniProtKB
Q16552
Attività biologica
Bioactivity assay: Production of IL-6 from mouse 3T3 cells, ED50 ≤10 ng/ml, bioactivity ≥1,0×10⁵ units/mg
Purezza
≥95%
Grado
RUO
Formulazione
0,1% Trifluoroacetic Acid (TFA)
Peso molecolare
15,7/31,3 kDa
Ricostituzione
Sterile water at 0,1 mg/ml
Condizioni di conservazione
−20 °C
Temperatura di spedizione
RT
Applicazioni testate
Bioassay
SHBT100-87-100UG
Vial
100 µG

1 * 100 µG
1 * 100 µG - SFr. 454.00
SFr. 454.00
1 * 100 µG
SFr. 454.00

Specifications
Cat. No.
SHBT100-87-100UG
Protein/peptide name
IL-17A
Protein synonyms
IL-17|CTLA-8
Protein/peptide type
Recombinant
Protein function
Cytokine
Specie
Human
Sorgente luminosa
E. coli
Coniugazione
Non coniugato
ID gene
Q16552
Sequenza
MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA
Protease-free
N
Senza animali
N
Esente da nucleasi
N
Senza corriere
Y
Privo di endotossine
N
Livello di endotossine
Low
Contenuto di endotossine
Endotoxin LAL (EU/µg) ≤0.1
UniProtKB
Q16552
Attività biologica
Bioactivity assay: Production of IL-6 from mouse 3T3 cells, ED50 ≤10 ng/ml, bioactivity ≥1,0×10⁵ units/mg
Purezza
≥95%
Grado
RUO
Formulazione
0,1% Trifluoroacetic Acid (TFA)
Peso molecolare
15,7/31,3 kDa
Ricostituzione
Sterile water at 0,1 mg/ml
Condizioni di conservazione
−20 °C
Temperatura di spedizione
RT
Applicazioni testate
Bioassay
SHBT100-87-500UG
Vial
500 µG

1 * 500 µG
1 * 500 µG - SFr. 1’960.00
SFr. 1’960.00
1 * 500 µG
SFr. 1’960.00

Specifications
Cat. No.
SHBT100-87-500UG
Protein/peptide name
IL-17A
Protein synonyms
IL-17|CTLA-8
Protein/peptide type
Recombinant
Protein function
Cytokine
Specie
Human
Sorgente luminosa
E. coli
Coniugazione
Non coniugato
ID gene
Q16552
Sequenza
MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA
Protease-free
N
Senza animali
N
Esente da nucleasi
N
Senza corriere
Y
Privo di endotossine
N
Livello di endotossine
Low
Contenuto di endotossine
Endotoxin LAL (EU/µg) ≤0.1
UniProtKB
Q16552
Attività biologica
Bioactivity assay: Production of IL-6 from mouse 3T3 cells, ED50 ≤10 ng/ml, bioactivity ≥1,0×10⁵ units/mg
Purezza
≥95%
Grado
RUO
Formulazione
0,1% Trifluoroacetic Acid (TFA)
Peso molecolare
15,7/31,3 kDa
Ricostituzione
Sterile water at 0,1 mg/ml
Condizioni di conservazione
−20 °C
Temperatura di spedizione
RT
Applicazioni testate
Bioassay
SHBT100-87-1MG
Vial
1 mg

1 * 1 mg
1 * 1 mg - SFr. 3’270.00
SFr. 3’270.00
1 * 1 mg
SFr. 3’270.00

Specifications
Cat. No.
SHBT100-87-1MG
Protein/peptide name
IL-17A
Protein synonyms
IL-17|CTLA-8
Protein/peptide type
Recombinant
Protein function
Cytokine
Specie
Human
Sorgente luminosa
E. coli
Coniugazione
Non coniugato
ID gene
Q16552
Sequenza
MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA
Protease-free
N
Senza animali
N
Esente da nucleasi
N
Senza corriere
Y
Privo di endotossine
N
Livello di endotossine
Low
Contenuto di endotossine
Endotoxin LAL (EU/µg) ≤0.1
UniProtKB
Q16552
Attività biologica
Bioactivity assay: Production of IL-6 from mouse 3T3 cells, ED50 ≤10 ng/ml, bioactivity ≥1,0×10⁵ units/mg
Purezza
≥95%
Grado
RUO
Formulazione
0,1% Trifluoroacetic Acid (TFA)
Peso molecolare
15,7/31,3 kDa
Ricostituzione
Sterile water at 0,1 mg/ml
Condizioni di conservazione
−20 °C
Temperatura di spedizione
RT
Applicazioni testate
Bioassay