Human Recombinant IL-8 (from E. coli)

Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-α, TGF-β and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells.

High quality
Low endotoxin
Affordable

PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-α and PDGFR-β.

: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.

: For research use only.

Coniugazione:
Non coniugato
Protein function:
Cytokine
Protein/peptide type:
Recombinant
Sorgente luminosa:
E. coli
Specie:
Human
Condizioni di conservazione:
−20 °C
Contenuto di endotossine:
Endotoxin LAL (EU/µg) ≤1
Attività biologica:
Bioactivity: No biological activity data is available at this time
ID gene:
P10145
Ricostituzione:
Sterile water at 0,1 mg/ml
Privo di endotossine:
N
Senza corriere:
Y
Protease-free:
N
Senza animali:
N
Protein synonyms:
neutrophil chemotactic factor|CXCL8
UniProtKB:
P10145
Protein/peptide name:
IL-8
Purezza:
≥95%
Peso molecolare:
8,9 kDa
Sequenza:
AVLPRSAKEL RCQCIKTYSK PFHPKFIKEL RVIESGPHCA NTEIIVKLSD GRELCLDPKE NWVQRVVEKF LKRAENS
Livello di endotossine:
Low
Formulazione:
10 mM sodium phosphate, pH 7,5
Esente da nucleasi:
N
Grado:
RUO
Temperatura di spedizione:
RT