Human recombinant FGF-22 (from E. coli)

About this item

Fibroblast growth factor 22 (FGF-22) is a mediator of synaptogenesis in the adult nervous system and functions to regulate synapse formation and maturation.

Produced from genetically modified E. coli
Monomeric protein, containing 149 amino acids

It is expressed in the inner hair cell and functions to maintain ribbon synapse number to protect functional hearing. In the hippocampus, FGF-22 promotes excitatory synapse formation through binding the FGFR2b and FGFR1b receptors. FGF-22 is also required for axonal circuit remodeling after spinal cord injury.

Delivery: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.

Caution: This product is for research use only and is not for use in humans.

Specifications

Coniugazione:
Non coniugato
Protein function:
Cytokine
Protein/peptide type:
Recombinant
Sorgente luminosa:
E. coli
Specie:
Human
Condizioni di conservazione:
–20 °C
Contenuto di endotossine:
Endotoxin LAL (EU/µg) ≤0,1
Attività biologica:
Bioactivity assay: Currently undetertmined, ED50 ≤Currenlty undetermined, Bioactivity ≥Currently undetermined
ID gene:
Q9HCT0
Ricostituzione:
Sterile water at 0.1 mg/ml
Privo di endotossine:
N
Senza corriere:
Y
Protease-free:
N
Senza animali:
N
Protein synonyms:
FGFM
Protein/peptide name:
FGF-22
Purezza:
≥95%
Peso molecolare:
17,3 kDa
Sequenza:
MTPSASRGPR SYPHLEGDVR WRRLFSSTHF FLRVDPGGRV QGTRWRHGQD SILEIRSVHV GVVVIKAVSS GFYVAMNRRG RLYGSRLYTVDCRFRERIEE NGHNTYASQR WRRRGQPMFL ALDRRGGPRP GGRTRRYHLS AHFLPVLVS
Livello di endotossine:
Low
Formulazione:
0,1% Trifluoroacetic Acid (TFA)
Esente da nucleasi:
N
Grado:
RUO
Temperatura di spedizione:
RT