Human Recombinant RANK LIGAND (from E. coli)
Supplier: Shenandoah Biotechnology
Certificates
About this item
Interleukin-1 receptor antagonist (IL-1RA) binds the interleukin 1 receptor (IL-1R) to antagonize interleukin 1 alpha and beta signaling. IL-1RA is secreted by immune cells, epithelial cells, hepatocytes, and adipocytes to inhibit IL-1-induced inflammation. IL-1RA therapy is used to treat auto-inflammatory diseases such as diabetes and rheumatoid arthritis.
- High quality
- Low endotoxin
- Affordable
Shenandoah Biotechnology is a manufacturer of research grade recombinant proteins typically used as cytokines, growth factors and chemokines in cell based assays and cell culture. Each production lot is tested for QA and the expected values for each product can be viewed under the product specifications tab.
Delivery: Certificate of Analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
Caution: For research use only.
Specifications
- Coniugazione:Non coniugato
- Protein function:Cytokine
- Protein/peptide type:Recombinant
- Sorgente luminosa:E. coli
- Specie:Human
- Condizioni di conservazione:−20 °C
- Contenuto di endotossine:Endotoxin LAL (EU/µg) ≤1
- Attività biologica:Bioactivity assay: Ability to induce bioluminescence in engineered RANKL bioassay cells , ED50 ≤50 ng/ml, bioactivity ≥2,0×10⁴ units/mg
- ID gene:O14788
- Ricostituzione:Sterile water at 0,1 mg/ml
- Privo di endotossine:N
- Senza corriere:Y
- Protease-free:N
- Senza animali:N
- Protein synonyms:OPGL|TNFSF11|ODF|TRANCE
- UniProtKB:O14788
- Protein/peptide name:RANK Ligand
- Purezza:≥95%
- Peso molecolare:19,7 kDa
- Sequenza:EKAMVDGSWL DLAKRSKLEA QPFAHLTINA TDIPSGSHKV SLSSWYHDRG WAKISNMTFS NGKLIVNQDG FYYLYANICF RHHETSGDLA TEYLQLMVYV TKTSIKIPSS HTLMKGGSTK YWSGNSEFHF YSINVGGFFK LRSGEEISIE VSNPSLLDPD QDATYFGAFK VRDID
- Livello di endotossine:Low
- Formulazione:10 mM sodium phosphate, pH 7,5
- Esente da nucleasi:N
- Grado:RUO
- Temperatura di spedizione:RT
- Applicazioni testate:Bioassay
Specifications
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