Interleukin 17F (IL-17F), a member of the IL-17 cytokine family, is secreted by activated CD4+ T cells and monocytes. IL-17F binds the IL-17 receptor related molecule, IL17RC, to promote the production of the interleukin 6 (IL-6), interleukin 8 (IL-8), and granulocyte macrophage colony-stimulating factor (GM-CSF) cytokines. IL-17F also functions to regulate matrix turnover rates, inhibit endothelial cell angiogenesis, and induce the endothelial cell expression of interleukin 2 (IL-2), monocyte chemoattractant protein-1 (MCP-1), and transforming growth factor beta 1 (TGF-β1).
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- Low Endotoxin
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A COA is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions. This product is for research use only and is not for use in humans.
- Coniugazione:Non coniugato
- Protein function:Cytokine
- Protein/peptide type:Recombinant
- Sorgente luminosa:E. coli
- Specie:Mouse
- Condizioni di conservazione:–20 °C
- Contenuto di endotossine:Endotoxin LAL (EU/µg) ≤1
- Attività biologica:Bioactivity: No biological activity data is available at this time
- ID gene:Q7TNI7
- Ricostituzione:Sterile water at 0.1 mg/ml
- Privo di endotossine:N
- Senza corriere:Y
- Protease-free:N
- Senza animali:N
- Protein/peptide name:IL-17F
- Purezza:≥95%
- Peso molecolare:15,0/30,0 kDa
- Sequenza:MRKNPKAGVP ALQKAGNCPP LEDNTVRVDI RIFNQNQGIS VPREFQNRSS SPWDYNITRD PHRFPSEIAE AQCRHSGCIN AQGQEDSTMN SVAIQQEILV LRREPQGCSN SFRLEKMLLK VGCTCVKPIV HQAA
- Livello di endotossine:Low
- Formulazione:0,1% Trifluoroacetic Acid (TFA)
- Esente da nucleasi:N
- Grado:RUO
- Temperatura di spedizione:RT