Human Recombinant IL-1RA (from E. coli)

Supplier: Shenandoah Biotechnology

Human Recombinant IL-1RA (from <i>E. coli</i>)

Supplier: Shenandoah Biotechnology

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Human Recombinant IL-1RA (from <i>E. coli</i>)

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About this item

Interleukin-1 receptor antagonist (IL-1RA) binds the interleukin 1 receptor (IL-1R) to antagonize interleukin 1 alpha and beta signaling. IL-1RA is secreted by immune cells, epithelial cells, hepatocytes, and adipocytes to inhibit IL-1-induced inflammation. IL-1RA therapy is used to treat auto-inflammatory diseases such as diabetes and rheumatoid arthritis.

High quality
Low endotoxin
Affordable

IL-1RA is secreted by immune cells, epithelial cells, hepatocytes, and adipocytes to inhibit IL-1-induced inflammation. IL-1RA therapy is used to treat auto-inflammatory diseases such as diabetes and rheumatoid arthritis.

Delivery information: A COA is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.

Caution: For research use only.

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Product Details & Documents

High quality
Low endotoxin
Affordable

Caution: For research use only.

Specifications for Product Family

Specifications

Catalog No:
SHBT100-195-20UG
SHBT100-195-100UG
SHBT100-195-250UG
SHBT100-195-500UG
SHBT100-195-1MG

Protein/peptide name:
IL-1RA
IL-1RA
IL-1RA
IL-1RA
IL-1RA

Protein synonyms:
IL-1F3|IL1RN
IL-1F3|IL1RN
IL-1F3|IL1RN
IL-1F3|IL1RN
IL-1F3|IL1RN

Protein/peptide type:
Recombinant
Recombinant
Recombinant
Recombinant
Recombinant

Protein function:
Cytokine
Cytokine
Cytokine
Cytokine
Cytokine

Specie:
Human
Human
Human
Human
Human

Sorgente luminosa:
E. coli
E. coli
E. coli
E. coli
E. coli

Coniugazione:
Non coniugato
Non coniugato
Non coniugato
Non coniugato
Non coniugato

ID gene:
P18510
P18510
P18510
P18510
P18510

Sequenza:
MRPSGRKSSK MQAFRIWDVN QKTFYLRNNQ LVAGYLQGPN VNLEEKIDVV PIEPHALFLG IHGGKMCLSC VKSGDETRLQ LEAVNITDLS ENRKQDKRFA FIRSDSGPTT SFESAACPGW FLCTAMEADQ PVSLTNMPDE GVMVTKFYFQ EDE
MRPSGRKSSK MQAFRIWDVN QKTFYLRNNQ LVAGYLQGPN VNLEEKIDVV PIEPHALFLG IHGGKMCLSC VKSGDETRLQ LEAVNITDLS ENRKQDKRFA FIRSDSGPTT SFESAACPGW FLCTAMEADQ PVSLTNMPDE GVMVTKFYFQ EDE
MRPSGRKSSK MQAFRIWDVN QKTFYLRNNQ LVAGYLQGPN VNLEEKIDVV PIEPHALFLG IHGGKMCLSC VKSGDETRLQ LEAVNITDLS ENRKQDKRFA FIRSDSGPTT SFESAACPGW FLCTAMEADQ PVSLTNMPDE GVMVTKFYFQ EDE
MRPSGRKSSK MQAFRIWDVN QKTFYLRNNQ LVAGYLQGPN VNLEEKIDVV PIEPHALFLG IHGGKMCLSC VKSGDETRLQ LEAVNITDLS ENRKQDKRFA FIRSDSGPTT SFESAACPGW FLCTAMEADQ PVSLTNMPDE GVMVTKFYFQ EDE
MRPSGRKSSK MQAFRIWDVN QKTFYLRNNQ LVAGYLQGPN VNLEEKIDVV PIEPHALFLG IHGGKMCLSC VKSGDETRLQ LEAVNITDLS ENRKQDKRFA FIRSDSGPTT SFESAACPGW FLCTAMEADQ PVSLTNMPDE GVMVTKFYFQ EDE

Protease-free:
N
N
N
N
N

Senza animali:
N
N
N
N
N

Esente da nucleasi:
N
N
N
N
N

Senza corriere:
Y
Y
Y
Y
Y

Privo di endotossine:
N
N
N
N
N

Livello di endotossine:
Low
Low
Low
Low
Low

Contenuto di endotossine:
Endotoxin LAL (EU/µg) ≤1
Endotoxin LAL (EU/µg) ≤1
Endotoxin LAL (EU/µg) ≤1
Endotoxin LAL (EU/µg) ≤1
Endotoxin LAL (EU/µg) ≤1

UniProtKB:
P18510
P18510
P18510
P18510
P18510

Attività biologica:
Bioactivity assay: Inhibition of human IL-1 alpha induced proliferation of D10,G4,1 cells, ED50 ≤50 ng/ml, bioactivity ≥2,0×10⁴ units/mg
Bioactivity assay: Inhibition of human IL-1 alpha induced proliferation of D10,G4,1 cells, ED50 ≤50 ng/ml, bioactivity ≥2,0×10⁴ units/mg
Bioactivity assay: Inhibition of human IL-1 alpha induced proliferation of D10,G4,1 cells, ED50 ≤50 ng/ml, bioactivity ≥2,0×10⁴ units/mg
Bioactivity assay: Inhibition of human IL-1 alpha induced proliferation of D10,G4,1 cells, ED50 ≤50 ng/ml, bioactivity ≥2,0×10⁴ units/mg
Bioactivity assay: Inhibition of human IL-1 alpha induced proliferation of D10,G4,1 cells, ED50 ≤50 ng/ml, bioactivity ≥2,0×10⁴ units/mg

Purezza:
≥95%
≥95%
≥95%
≥95%
≥95%

Grado:
RUO
RUO
RUO
RUO
RUO

Formulazione:
10 mM sodium phosphate, pH 7,5
10 mM sodium phosphate, pH 7,5
10 mM sodium phosphate, pH 7,5
10 mM sodium phosphate, pH 7,5
10 mM sodium phosphate, pH 7,5

Peso molecolare:
17,3 kDa
17,3 kDa
17,3 kDa
17,3 kDa
17,3 kDa

Ricostituzione:
Sterile water at 0,1 mg/ml
Sterile water at 0,1 mg/ml
Sterile water at 0,1 mg/ml
Sterile water at 0,1 mg/ml
Sterile water at 0,1 mg/ml

Condizioni di conservazione:
−20 °C
−20 °C
−20 °C
−20 °C
−20 °C

Temperatura di spedizione:
RT
RT
RT
RT
RT

Applicazioni testate:
Bioassay
Bioassay
Bioassay
Bioassay
Bioassay

Specifications

Product Family Options

Product Information

Tipo di conf.
Conf
Availability
Price
SHBT100-195-20UG
Vial
20 µG
Log in for availability
Log in for availability
1 * 20 µG
1 * 20 µG - 73.00 SFr.
73.00 SFr.
1 * 20 µG
73.00 SFr.
Specifications:
More
Specifications
Cat. No.
SHBT100-195-20UG
Protein/peptide name
IL-1RA
Protein synonyms
IL-1F3|IL1RN
Protein/peptide type
Recombinant
Protein function
Cytokine
Specie
Human
Sorgente luminosa
E. coli
Coniugazione
Non coniugato
ID gene
P18510
Sequenza
MRPSGRKSSK MQAFRIWDVN QKTFYLRNNQ LVAGYLQGPN VNLEEKIDVV PIEPHALFLG IHGGKMCLSC VKSGDETRLQ LEAVNITDLS ENRKQDKRFA FIRSDSGPTT SFESAACPGW FLCTAMEADQ PVSLTNMPDE GVMVTKFYFQ EDE
Protease-free
N
Senza animali
N
Esente da nucleasi
N
Senza corriere
Y
Privo di endotossine
N
Livello di endotossine
Low
Contenuto di endotossine
Endotoxin LAL (EU/µg) ≤1
UniProtKB
P18510
Attività biologica
Bioactivity assay: Inhibition of human IL-1 alpha induced proliferation of D10,G4,1 cells, ED50 ≤50 ng/ml, bioactivity ≥2,0×10⁴ units/mg
Purezza
≥95%
Grado
RUO
Formulazione
10 mM sodium phosphate, pH 7,5
Peso molecolare
17,3 kDa
Ricostituzione
Sterile water at 0,1 mg/ml
Condizioni di conservazione
−20 °C
Temperatura di spedizione
RT
Applicazioni testate
Bioassay
SHBT100-195-100UG
Vial
100 µG
Log in for availability
Log in for availability
1 * 100 µG
1 * 100 µG - 182.00 SFr.
182.00 SFr.
1 * 100 µG
182.00 SFr.
Specifications:
More
Specifications
Cat. No.
SHBT100-195-100UG
Protein/peptide name
IL-1RA
Protein synonyms
IL-1F3|IL1RN
Protein/peptide type
Recombinant
Protein function
Cytokine
Specie
Human
Sorgente luminosa
E. coli
Coniugazione
Non coniugato
ID gene
P18510
Sequenza
MRPSGRKSSK MQAFRIWDVN QKTFYLRNNQ LVAGYLQGPN VNLEEKIDVV PIEPHALFLG IHGGKMCLSC VKSGDETRLQ LEAVNITDLS ENRKQDKRFA FIRSDSGPTT SFESAACPGW FLCTAMEADQ PVSLTNMPDE GVMVTKFYFQ EDE
Protease-free
N
Senza animali
N
Esente da nucleasi
N
Senza corriere
Y
Privo di endotossine
N
Livello di endotossine
Low
Contenuto di endotossine
Endotoxin LAL (EU/µg) ≤1
UniProtKB
P18510
Attività biologica
Bioactivity assay: Inhibition of human IL-1 alpha induced proliferation of D10,G4,1 cells, ED50 ≤50 ng/ml, bioactivity ≥2,0×10⁴ units/mg
Purezza
≥95%
Grado
RUO
Formulazione
10 mM sodium phosphate, pH 7,5
Peso molecolare
17,3 kDa
Ricostituzione
Sterile water at 0,1 mg/ml
Condizioni di conservazione
−20 °C
Temperatura di spedizione
RT
Applicazioni testate
Bioassay
SHBT100-195-250UG
Vial
250 µG
Log in for availability
Log in for availability
1 * 250 µG
1 * 250 µG - 454.00 SFr.
454.00 SFr.
1 * 250 µG
454.00 SFr.
Specifications:
More
Specifications
Cat. No.
SHBT100-195-250UG
Protein/peptide name
IL-1RA
Protein synonyms
IL-1F3|IL1RN
Protein/peptide type
Recombinant
Protein function
Cytokine
Specie
Human
Sorgente luminosa
E. coli
Coniugazione
Non coniugato
ID gene
P18510
Sequenza
MRPSGRKSSK MQAFRIWDVN QKTFYLRNNQ LVAGYLQGPN VNLEEKIDVV PIEPHALFLG IHGGKMCLSC VKSGDETRLQ LEAVNITDLS ENRKQDKRFA FIRSDSGPTT SFESAACPGW FLCTAMEADQ PVSLTNMPDE GVMVTKFYFQ EDE
Protease-free
N
Senza animali
N
Esente da nucleasi
N
Senza corriere
Y
Privo di endotossine
N
Livello di endotossine
Low
Contenuto di endotossine
Endotoxin LAL (EU/µg) ≤1
UniProtKB
P18510
Attività biologica
Bioactivity assay: Inhibition of human IL-1 alpha induced proliferation of D10,G4,1 cells, ED50 ≤50 ng/ml, bioactivity ≥2,0×10⁴ units/mg
Purezza
≥95%
Grado
RUO
Formulazione
10 mM sodium phosphate, pH 7,5
Peso molecolare
17,3 kDa
Ricostituzione
Sterile water at 0,1 mg/ml
Condizioni di conservazione
−20 °C
Temperatura di spedizione
RT
Applicazioni testate
Bioassay
SHBT100-195-500UG
Vial
500 µG
Log in for availability
Log in for availability
1 * 500 µG
1 * 500 µG - 786.00 SFr.
786.00 SFr.
1 * 500 µG
786.00 SFr.
Specifications:
More
Specifications
Cat. No.
SHBT100-195-500UG
Protein/peptide name
IL-1RA
Protein synonyms
IL-1F3|IL1RN
Protein/peptide type
Recombinant
Protein function
Cytokine
Specie
Human
Sorgente luminosa
E. coli
Coniugazione
Non coniugato
ID gene
P18510
Sequenza
MRPSGRKSSK MQAFRIWDVN QKTFYLRNNQ LVAGYLQGPN VNLEEKIDVV PIEPHALFLG IHGGKMCLSC VKSGDETRLQ LEAVNITDLS ENRKQDKRFA FIRSDSGPTT SFESAACPGW FLCTAMEADQ PVSLTNMPDE GVMVTKFYFQ EDE
Protease-free
N
Senza animali
N
Esente da nucleasi
N
Senza corriere
Y
Privo di endotossine
N
Livello di endotossine
Low
Contenuto di endotossine
Endotoxin LAL (EU/µg) ≤1
UniProtKB
P18510
Attività biologica
Bioactivity assay: Inhibition of human IL-1 alpha induced proliferation of D10,G4,1 cells, ED50 ≤50 ng/ml, bioactivity ≥2,0×10⁴ units/mg
Purezza
≥95%
Grado
RUO
Formulazione
10 mM sodium phosphate, pH 7,5
Peso molecolare
17,3 kDa
Ricostituzione
Sterile water at 0,1 mg/ml
Condizioni di conservazione
−20 °C
Temperatura di spedizione
RT
Applicazioni testate
Bioassay
SHBT100-195-1MG
Vial
1 mg
Log in for availability
Log in for availability
1 * 1 mg
1 * 1 mg - 1 210.00 SFr.
1 210.00 SFr.
1 * 1 mg
1 210.00 SFr.
Specifications:
More
Specifications
Cat. No.
SHBT100-195-1MG
Protein/peptide name
IL-1RA
Protein synonyms
IL-1F3|IL1RN
Protein/peptide type
Recombinant
Protein function
Cytokine
Specie
Human
Sorgente luminosa
E. coli
Coniugazione
Non coniugato
ID gene
P18510
Sequenza
MRPSGRKSSK MQAFRIWDVN QKTFYLRNNQ LVAGYLQGPN VNLEEKIDVV PIEPHALFLG IHGGKMCLSC VKSGDETRLQ LEAVNITDLS ENRKQDKRFA FIRSDSGPTT SFESAACPGW FLCTAMEADQ PVSLTNMPDE GVMVTKFYFQ EDE
Protease-free
N
Senza animali
N
Esente da nucleasi
N
Senza corriere
Y
Privo di endotossine
N
Livello di endotossine
Low
Contenuto di endotossine
Endotoxin LAL (EU/µg) ≤1
UniProtKB
P18510
Attività biologica
Bioactivity assay: Inhibition of human IL-1 alpha induced proliferation of D10,G4,1 cells, ED50 ≤50 ng/ml, bioactivity ≥2,0×10⁴ units/mg
Purezza
≥95%
Grado
RUO
Formulazione
10 mM sodium phosphate, pH 7,5
Peso molecolare
17,3 kDa
Ricostituzione
Sterile water at 0,1 mg/ml
Condizioni di conservazione
−20 °C
Temperatura di spedizione
RT
Applicazioni testate
Bioassay