Human recombinant sulphotransferase 1A1 (from E. coli)
Codice catalogo PRSI92-136
Nome del fornitore: ProSci Inc.
Numero CAS:
Specifiche
- Conf:50 µG
- Tipo di enzima:Recombinant
- Sorgente luminosa:E. coli
- Specie:Human
- Sequenza tag:N-6 His tag
- Condizioni di conservazione:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
- Nome dell'enzima:Sulfotransferase 1A1
- Purezza:>95% as determined by reducing SDS-PAGE
- Peso molecolare:35.5 kD
- Sequenza:Met1-Leu295
- Formulazione:Supplied as a 0.2 µm filtered solution of 20 mM Tris, 150 mM NaCl,1 mM EDTA,pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Applicazioni testate:Bioassay
Specifiche
Informazioni su questo articolo
Sulfotransferase 1A1 (SULT1A1) is a cytosolic sulfotransferases that is expressed in the liver, lung, adrenal, brain, platelets, and skin. SULT1A1 is a phenol sulfotransferases with thermostable enzyme activity. SULT1A1 utilises 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyse the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. It is responsible for the sulfonation and activation of minoxidil. SULT1A1 mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk.
Fusion-Tag: N-6 His tag
This recombinant protein can be used for biological assays. For research use only.