Specifications
- Conf:50 µG
- Tipo di enzima:Recombinant
- Sorgente luminosa:Cells
- Specie:Human
- Sequenza tag:C-6 His tag
- Condizioni di conservazione:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
- Nome dell'enzima:Prostaglandin-D2 Synthase
- Purezza:>95% as determined by reducing SDS-PAGE
- Peso molecolare:19.7 kD
- Sequenza:Ala23-Gln190
- Formulazione:Supplied as a 0.2 µm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 10% Glycerol,pH 7.5. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Applicazioni testate:Bioassay
Specifications
About this item
Prostaglandin-H2 D-Isomerase (PTGDS) belongs to the Lipocalin family of calycin superfamily. PTGDS is preferentially expressed in the brain. PTGDS catalyses the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. PTGDS is involved in a variety of CNS functions, such as sedation, REM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. PTGDS binds small non-substrate lipophilic molecules and may act as a scavenger for harmful hydrophopic molecules and a secretory retinoid and thyroid hormone transporter. It possibly participates in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor, blood-testis barrier, the central nervous system and male reproductive system.
Fusion-Tag: C-6 His tag
This recombinant protein can be used for biological assays. For research use only.