Human recombinant PPIase (from E. coli)
Codice catalogo PRSI91-271
Nome del fornitore: ProSci Inc.
Numero CAS:
Specifiche
- Conf:50 µG
- Tipo di enzima:Recombinant
- Sorgente luminosa:E. coli
- Specie:Human
- Sequenza tag:N-6 His tag
- Condizioni di conservazione:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
- Nome dell'enzima:PPIase
- Purezza:>95% as determined by reducing SDS-PAGE
- Peso molecolare:20.4 kD
- Sequenza:Met1-Gly166
- Formulazione:Supplied as a 0.2 µm filtered solution of 20 mM TrisHCl, pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Applicazioni testate:Bioassay
Specifiche
Informazioni su questo articolo
Peptidyl-Prolyl Cis-Trans Isomerase-Like 1 (PPIase) belongs to the cyclophilin-type PPIase family. PPIases can accelerate the folding of proteins and catalyze the cis-trans isomerisaion of proline imidic peptide bonds in oligopeptides. PPIase is a ubiquitous protein and has highly expression in heart ,skeletal and muscle. PPIase contains a PPIase cyclophilin-type domain and four Cyclosporin A binding regions. PPIase might play an important role in proliferation of cancer cells through modulation of phosphorylation of stathmin. It is suggested that PPIase can act as as a novel molecular target for colon-cancer therapy.
Fusion-Tag: N-6 His tag
This recombinant protein can be used for biological assays. For research use only.