Specifications
- Conf:50 µG
- Protein/peptide type:Recombinant
- Sorgente luminosa:E. coli
- Specie:Mouse
- Condizioni di conservazione:Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
- Protein synonyms:Scya21|TCA4|Beta-Chemokine Exodus-2|6Ckine|Scya21a|Thymus-Derived Chemotactic Agent 4|C-C Motif Chemokine 21a|Small-Inducible Cytokine A21a|Ccl21a
- Protein/peptide name:CCL21A
- Purezza:> 95% as determined by reducing SDS-PAGE
- Peso molecolare:12 kD
- Sequenza:Ser24-Gly133
- Formulazione:Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Applicazioni testate:Bioassay
Specifications
About this item
C-C Motif Chemokine 21a (CCL21a) is a small secreted cytokine that belongs to the intercrine beta (CC chemokine) family. Mouse CCL21 cDNA encodes a 133 amino acid residue protein with a 23 residue signal peptide that is cleaved to generate the 110 residue mature protein. Mouse CCL21 has three forms while CCL21a has Ser-65. CCL21 elicits its effects by binding to a cell surface chemokine receptor known as CCR7 and CXCR3. Mouse CCL21 inhibits hemopoiesis and stimulates chemotaxis. It has chemotactic function in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Mouse CCL21 shows preferential activity towards naive T-cells and may play a role in mediating homing of lymphocytes to secondary lymphoid organs.
This recombinant protein can be used for biological assays. For research use only.