- Tipo anticorpo:Primary
- Tipo di anticorpi:CD33 molecule
- Simbolo dell'antigene:CD33
- Clonalità:Policlonale
- Coniugazione:FITC (Fluoresceina Isotiocionato)
- Ospite:Rabbit
- ImmunoChimica:Yes
- Isotipo:IgG
- Reattività:Human
- Assorbimento incrociato:No
- Forma:liquid
- ID gene:945
- Sinomini antigene:SIGLEC-3|SIGLEC3|CD33|Siglec-3|Myeloid cell surface antigen CD33|Sialic acid-binding Ig-like lectin 3|p67
- Tampone di conservazione:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Temperatura di conservazione:Store at 4°C for 12 months
- Concentrazione:1 μg/μl
- Temperatura di spedizione:4°C
- Immunogeno:285-335/364
- Purificazione:Purified by Protein A
- Conf:100 µl
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: CD33
Clonality: Polyclonal
Clone: 0
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: