Specifiche
- Tipo anticorpo:Primary
- Simbolo dell'antigene:NAC1/BTBD14B
- Clonalità:Policlonale
- Coniugazione:Alexa Fluor® 647
- Ospite:Rabbit
- ImmunoChimica:Yes
- Isotipo:IgG
- Reattività:Human,Rat,Mouse
- Assorbimento incrociato:No
- Forma:liquid
- ID gene:112939
- Tampone di conservazione:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Temperatura di conservazione:Store at 4°C for 12 months
- Concentrazione:1 μg/μl
- Temperatura di spedizione:4°C
- Purificazione:Purified by Protein A
- Conf:100 µl
Specifiche
Informazioni su questo articolo
NAC1 is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. BTBD14B (BTB/POZ domain-containing protein 14B), also known as NACC1 (nucleus accumbens associated 1), BEND8 or NAC1, is a 527 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one BTB (POZ) domain. Existing as a homooligomer that interacts with HDAC3 and HDAC4, BTBD14B functions as a transcriptional repressor that influences the transcriptional activity of CRIF1 and is required for proteasome recruitment to the nucleus and cytoplasm in dendritic spines. BTBD14B is overexpressed in multiple carcinomas, suggesting a role in tumor development and metastasis.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: NAC1/BTBD14B
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat