Specifiche
- Tipo anticorpo:Primary
- Tipo di anticorpi:Sparc/Osteonectin, Cwcv And Kazal-Like Domains Proteoglycan 2
- Simbolo dell'antigene:SPOCK2
- Clonalità:Policlonale
- Coniugazione:FITC (Fluoresceina Isotiocionato)
- Ospite:Rabbit
- ImmunoChimica:Yes
- Isotipo:IgG
- Reattività:Human,Rat,Mouse
- Assorbimento incrociato:No
- Forma:liquid
- Sinomini antigene:CWCV|TICN2_HUMAN.|Kazal-like domains proteoglycan 2|Sparc/osteonectin cwcv and kazal like domains proteoglycan 2|FLJ97039|SPOCK 2|Sparc/osteonectin cwcv and kazal like domains proteoglycan testican 2|TICN 2|TICN2|Testican2|KIAA0275|Testican-2|Spock2|SPARC/osteonectin
- Tampone di conservazione:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Temperatura di conservazione:Store at 4°C for 12 months
- Concentrazione:1 μg/μl
- Temperatura di spedizione:4°C
- Purificazione:Purified by Protein A
- Conf:100 µl
Specifiche
Informazioni su questo articolo
The Testican family, also designated the BM-40/SPARC/osteonectin family, is composed of highly conserved, extracellular, calcium-binding, sulfate proteoglycans. Expression of Testicans is detected in a variety of tissues, but is most abundant in brain. Family members include Testican-1, Testican-2, Testican-3 and an amino-terminal splice variant of Testican-3, designated N-Tes. Most Testicans inhibit MT-MMPs, thereby inhibiting the activity of pro-MMP-2. Testican-2 is expressed in the central nervous system (CNS), with widespread expression in the olfactory bulb, cerebral cortex, thalamus, hippocampus, cerebellum and medulla, and is also found in lung and testis. Testican-2 is unique in that it actually abolishes the inhibition of MT-MMPs by other testican family members and specifically inactivates N-Tes by binding to its COOH-terminal extracellular calcium-binding domain. Testican-2 halts neurite growth from cerebellar neurons and may be involved in regu-lating the development of the CNS.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: SPOCK2
Clonality: Polyclonal
Clone:
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat