Human ACE2 ELISA kit

Human ACE2 ELISA Kit is used for quantitative detection of human ACE2 in cell culture supernates, serum and plasma (heparin, EDTA).

Angiotensin I converting enzyme 2 (ACE 2) is a protein belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. By sequence similarity to a sequence in GenBank, this gene is mapped to Xp22.2. This secreted protein catalyses the cleavage of angiotensin I into angiotensin 1 - 9, and angiotensin II into the vasodilator angiotensin 1 to 7.

The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.