This antibody recognizes a 27 kDa protein, identified as the p27Kip1, a cell cycle regulatory mitotic inhibitor. Its epitope spans between aa 83-204 of p27. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene. This MAb co-precipitates cdk4 in complex p27Kip1 and is excellent for staining of formalin-fixed tissues.
Type: Primary
Antigen: CDKN1B
Clonality: Monoclonal
Clone: SX53G8
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG
Reactivity: Human, Monkey, Mouse, Rat
- Catalog No:
- BNC881237-100
- BNC881237-500
- Simbolo dell'antigene:
- CDKN1B
- CDKN1B
- Tipo di anticorpi:
- Cyclin-dependent kinase inhibitor 1B
- Cyclin-dependent kinase inhibitor 1B
- Sinomini antigene:
- CDKN1B|CDKN4|KIP1|Cyclin-dependent kinase inhibitor p27 Kip1|MEN1B|Cyclin Dependent Kinase Inhibitor 1B|MEN4
- CDKN1B|CDKN4|KIP1|Cyclin-dependent kinase inhibitor p27 Kip1|MEN1B|Cyclin Dependent Kinase Inhibitor 1B|MEN4
- Tipo anticorpo:
- Primary
- Primary
- Clonalità:
- Monoclonale
- Monoclonale
- Coniugazione:
- CF® 488A
- CF® 488A
- Clone:
- Clone SX53G8
- Clone SX53G8
- Reattività:
- Monkey, Human, Rat, Mouse
- Monkey, Human, Rat, Mouse
- Ospite:
- Mouse
- Mouse
- ID gene:
- 238990
- 238990
- Isotipo:
- IgG
- IgG
- Western blot:
- Yes
- Yes
- ImmunoChimica:
- Yes
- Yes
- ImmunoFluorescenza:
- Yes
- Yes
- Concentrazione:
- 0,1 mg/ml
- 0,1 mg/ml
- Tampone di conservazione:
- PBS/0,1% BSA/0,05% azide
- PBS/0,1% BSA/0,05% azide
: VWR Collection
: VWR Collection
: VWR Chemicals
: VWR Chemicals
: VWR Collection
: KIMBERLY CLARK
: VWR Collection
: VWR Collection