Spécifications

Tipo anticorpo:
Primary
Tipo di anticorpi:
Receptor Accessory Protein 1
Simbolo dell'antigene:
REEP1
Clonalità:
Policlonale
Coniugazione:
Non coniugato
Ospite:
Rabbit
ImmunoChimica:
Yes
Isotipo:
IgG
Reattività:
Human,
Rat,
Mouse
Western blot:
Yes
Forma:
liquid
Sinomini antigene:
REEP1_HUMAN|Receptor expression-enhancing protein 1|C2orf23|FLJ13110|Reep1|Chromosome 2 open reading frame 23|Receptor accessory protein 1|SPG31.
Tampone di conservazione:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0,09% sodium azide. Store at -20°C for 12 months.
Concentrazione:
1 ug/ul
Temperatura di spedizione:
4 °C
Purificazione:
Purified by Protein A.
Taglia:
100 μg
Conf:
100 µl

Spécifications

À propos de cet article

Transport of G protein-coupled receptors (GPCRs) to the cell surface membrane is critical for receptor-ligand recognition. Mammalian GPCR odorant receptors (ORs), when heterologously expressed in cells, are poorly expressed on the cell surface. REEP1 (receptor expression-enhancing protein 1), is a 201 amino acid multi-pass mitochondrion membrane protein that belongs to the DP1 family. REEP1 interacts with odorant receptor proteins and may enhance the cell surface expression of odorant receptors. Mutations in the REEP1 gene are the third most common cause of hereditary spastic paraplegia (HSP) after spastin and atlastin gene mutations. Mutations in the REEP1 gene also cause spastic paraplegia autosomal dominant type 31, a neurodegenerative disorder. The REEP1 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, A.thaliana and rice, and maps to human chromosome 2p11.2.

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Type: Primary
Antigen: REEP1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat