- Tipo anticorpo:Primary
- Tipo di anticorpi:Beta-nerve growth factor
- Simbolo dell'antigene:beta NGF
- Clonalità:Policlonale
- Coniugazione:Non coniugato
- ELISA:Yes
- Ospite:Sheep
- ImmunoChimica:Yes
- Isotipo:IgG
- Reattività:Birds,Human,Rat,Mouse
- Western blot:Yes
- Epitopo:Multiple points of reactivity likely because of the polyclonal nature of the antibody
- Assorbimento incrociato:No
- Neutralisation:Yes
- Formato:Lyophilized
- Immunogeno:Native mouse beta NGF purified from submaxillary salivary gland (95% purity by PAGE)
- Taglia:50 µg
- Conf:50 µG
FUNCTION: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons. SUBUNIT: Homodimer, associated by noncovalent forces. SUBCELLULAR LOCATION: Secreted protein. SIMILARITY: Belongs to the NGF-beta family.
A cross reactivity of less than 1% to recombinant human BDNF, NT3, NT4/5 by ELISA has been shown.
Application Information:
IHC, 1-site ELISA, WB, immunoblot, inhibition of biological activity. A concentration of 1-3 µg/ml is recommended for IHC, western blot and immunoblot, ELISA, inhibition of biological activity in vitro. Use neat for in vivo studies at 2-10 µg/ml (ED50). This antiserum completely inhibits neuronal survival and the outgrowth actions of murine NGF in chicken DRG in vitro. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: beta NGF
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: Multiple points of reactivity likely because of the polyclonal nature of the antibody
Host: Sheep
Isotype: IgG
Reactivity: Mouse, Rat, Human, Avis