- Tipo anticorpo:Primary
- Tipo di anticorpi:Protein tyrosine phosphatase, non-receptor type 14
- Simbolo dell'antigene:PTPN14
- Clonalità:Monoclonale
- Clone:T40-AF7C8
- Coniugazione:Non coniugato
- Ospite:Mouse
- Isotipo:IgG1
- Reattività:Human
- Western blot:Yes
- Assorbimento incrociato:none
- ID gene:5784
- Sinomini antigene:PEZ|PTP36
- Temperatura di conservazione:Store for 1 year at –20 °C from date of shipment
- Temperatura di spedizione:Ice
- Immunogeno:Recombinant human protein purified from E.coli
- Purificazione:Ammonium sulfate precipitation
- Taglia:100 µl
- Conf:0,1 mL
Protein-tyrosine phosphatase 14 (PTPN14/PTPD2/PEZ) is a 130kDa multidomain cytosolic protein, and belongs to the NT6 subtype of PTPs.
It is characterized by an N-terminal FERM domain (Band 4.1, ezrin, radixin, moesin homology) and a C-terminal PTP domain. Pez(Phosphatase with ezrin domain) may play a role in regulating endothelial cell proliferation during vascular injury and angiogenesis. B-Catenin, a central component of adherens junctions, has been identified as a PTPN14 substrate. TGF, which inhibits cell proliferation but not migration, also inhibits translocation of PTPN14 from the cytosol to the nucleus.
Western Blot: 1:500;
Type: Primary
Antigen: PTPN14 (protein tyrosine phosphatase, non-receptor type 14)
Clonality: Monoclonal
Clone: T40-AF7C8
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1 Kappa
Reactivity: Human