Specifications
- Tipo anticorpo:Primary
- Tipo di anticorpi:Cofilin 1
- Simbolo dell'antigene:CFL1
- Clonalità:Monoclonale
- Clone:AF2C2
- Coniugazione:Non coniugato
- ELISA:Yes
- Ospite:Mouse
- Isotipo:IgG2a
- Reattività:Human,Rat,Mouse
- Western blot:Yes
- Assorbimento incrociato:none
- ID gene:1072
- Sinomini antigene:HEL-S-15|cofilin|CFL
- Temperatura di conservazione:Store for 1 year at –20 °C from date of shipment
- Concentrazione:4 mg/ml
- Temperatura di spedizione:Ice
- Immunogeno:Recombinant human protein purified from E.coli (His-cofilin)
- Purificazione:Protein G purified
- Taglia:100 µl
- Conf:0,1 mL
Specifications
About this item
Cofilin belongs to a family of related proteins with similar biochemical activities called the actin depolymerizing factor (ADF)/cofilin family.
ADF/cofilins play an important role in cytokinesis , endocytosis, and in the development of all embryonic tissues.
Cofilin is a small ubiquitous protein (~19 kDa) that is able to bind both G-actin (monomeric) and F-actin(filamentous actin). Cofilin promotes the regeneration of actin filaments by severing pre-existing filaments.
LIMK or TESK play a central role in the regulation of the actin cytoskeleton by phosphorylating cofilin on Ser3. Phosphorylation of cofilin at Ser3 inhibits its ability to bind to actin.
Western Blot: 4.0ug/ml;
Type: Primary
Antigen: CFL1 (cofilin 1 (non-muscle))
Clonality: Monoclonal
Clone: AF2C2
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2a Kappa
Reactivity: Human, Mouse, Rat