Fibronectin (FN) exists in two main forms: 1) as a soluble glycoprotein in blood plasma (plasma FN), and 2) as an insoluble glycoprotein in tissue extracellular matrices (cellular FN). Many different cell types synthesize fibronectin and secrete it as a disulfide-bonded dimer composed of 230–270 kDa subunits. FN is one of the largest multi-domain proteins that interact with a variety of macromolecules like heparin, collagen /gelatin, and fibrin. FN is involved in many cellular processes, including tissue repair, embryogenesis, blood clotting, and cell migration/ adhesion and so can be used as a therapeutic agent for wound healing. In addition, its age-dependent increase in plasma and tissues may be accompanied in pathological states, especially in tumor growth, by its proteolytic breakdown.

Western Blot: 1.0ug/ml; Immunoprecipitation: 2.0ug;

Type: Primary
Antigen: Fibronectin (fibronectin)
Clonality: Monoclonal
Clone: 23C9
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2b Kappa
Reactivity: Human