- Tipo anticorpo:Primary
- Tipo di anticorpi:Alpha-2-macroglobulin
- Simbolo dell'antigene:A2M
- Clonalità:Monoclonale
- Clone:9A3
- Coniugazione:Non coniugato
- ELISA:Yes
- Ospite:Mouse
- ImmunoPrecipitazione:Yes
- Isotipo:IgG2b
- Reattività:Human
- Assorbimento incrociato:none
- ID gene:2
- Sinomini antigene:S863-7|CPAMD5|FWP007|A2MD
- Temperatura di conservazione:Store for 1 year at –20 °C from date of shipment
- Temperatura di spedizione:Ice
- Immunogeno:alpha 2-macroglobulin protein purified from Human plasma
- Purificazione:Ammonium sulfate precipitation
- Taglia:100 µl
- Conf:0,1 mL
α2-Macroglobulin (α2M), is a 720-kDa homotetrameric glycoprotein composed of four identical 180 kDa subunit. α2M shares with other α-macroglobulins, like the complement components C3 and C4 and the pregnancy zone protein PZP, an extraordinary binding capacity for a variety of ligands. This allows the α-macroglobulins to serve as humoral defense barriers against foreign peptides in the plasma. α2M interacts and captures virtually any proteinase, often referred to as a panprotease inhibitor. In the brain of Alzheimer's disease (AD) patients, α2M also has been localized to diffuse amyloid plaques, supporting an important role for α2M in AD etiopathology.
Immunoprecipitation: 1ug;
Type: Primary
Antigen: A2M (alpha-2-macroglobulin)
Clonality: Monoclonal
Clone: 9A3
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2b Kappa
Reactivity: Human