- Tipo anticorpo:Primary
- Tipo di anticorpi:cyclin-dependent kinase 5
- Simbolo dell'antigene:CDK5
- Clonalità:Monoclonale
- Clone:8A1
- Coniugazione:Non coniugato
- ELISA:Yes
- Ospite:Mouse
- ImmunoPrecipitazione:Yes
- Isotipo:IgG2b
- Reattività:Human,Rat,Mouse
- Western blot:Yes
- Assorbimento incrociato:none
- ID gene:1020
- Sinomini antigene:PSSALRE|LIS7
- Temperatura di conservazione:Store for 1 year at –20 °C from date of shipment
- Temperatura di spedizione:Ice
- Immunogeno:His-tagged recombinant human CDK5 protein purified from Baculovirus expressed insect cells.
- Purificazione:Ammonium sulfate precipitation
- Taglia:100 µl
- Conf:0,1 mL
Cyclin-dependent kinase-5 (CDK5) is a member of the cyclin-dependent kinase family of serine/threonine kinases. Its mRNA and protein are expressed in kidney, testes, and ovary. And Its activity is detected almost exclusively in brain extracts.
Similar to other Cdks, monomeric Cdk5 displays no enzymatic activity, but Cdk5 is not activated by cyclins. Instead, Cdk5 activity requires association with one of two brain-specific regulatory subunits called p35 and p39. The two activators regulate the spatial and temporal expression of active Cdk5 to restrict its activity primarily to post-mitotic neurons.
Western Blot: 1:1000 ~ 2000; Immunoprecipitation: 2 ?l;
Type: Primary
Antigen: CDK5 (cyclin-dependent kinase 5)
Clonality: Monoclonal
Clone: 8A1
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2b Kappa
Reactivity: Human, Mouse, Rat