Specifiche
- Tipo anticorpo:Primary
- Tipo di anticorpi:Methionine sulfoxide reductase A
- Simbolo dell'antigene:MSRA
- Clonalità:Monoclonale
- Clone:5B5
- Coniugazione:Non coniugato
- Ospite:Mouse
- ImmunoChimica:Yes
- ImmunoPrecipitazione:Yes
- Isotipo:IgG2b
- Reattività:Human,Rat
- Assorbimento incrociato:none
- ID gene:4482
- Sinomini antigene:PMSR
- Temperatura di conservazione:Store for 1 year at –20 °C from date of shipment
- Temperatura di spedizione:Ice
- Immunogeno:Recombinant human protein purified from E.coli
- Purificazione:Ammonium sulfate precipitation
- Taglia:100 µl
- Conf:0,1 mL
Specifiche
Informazioni su questo articolo
Methionine sulfoxide reductase (MsrA) reduces methionine sulfoxide (MetO) residues in proteins and free MetO to Methionine (Met). The catalytic activity of MsrA is dependent of bound metal and cofactors but it requires reducing equivalents from either DTT or a thioredoxin-regenerating system. MsrA plays an essential role in protecting cells against oxidative damage. The substrates of MsrA include calmodulin, HIV protease and 1-proteinase-inhibitor (1-3). Recent studies indicate that there is a connection between MsrA and Alzheimer’s disease in mammals (4).
Immunoprecipitation: 1-2 ?l; Immunohistochemistry: Paraffin-embedded sections;
Type: Primary
Antigen: MSRA (methionine sulfoxide reductase A)
Clonality: Monoclonal
Clone: 5B5
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2b Kappa
Reactivity: Human, Rat