- Tipo anticorpo:Primary
- Tipo di anticorpi:amphiphysin
- Simbolo dell'antigene:AMPH
- Clonalità:Monoclonale
- Clone:C14-23
- Coniugazione:Non coniugato
- Ospite:Mouse
- ImmunoChimica:Yes
- ImmunoPrecipitazione:Yes
- Isotipo:IgG1
- Reattività:Rat,Mouse
- Western blot:Yes
- Assorbimento incrociato:none
- ID gene:273
- Sinomini antigene:AMPH1
- Temperatura di conservazione:Store for 1 year at –20 °C from date of shipment
- Concentrazione:1 mg/ml
- Temperatura di spedizione:Ice
- Immunogeno:Recombinant human GST-fragment protein (320-696AA) purified from E.coli
- Purificazione:Protein G purified
- Taglia:100 µl
- Conf:0,1 mL
Amphiphysins, members of the BAR (Bin-Amphiphysin-Rvsp) protein super family, play a key role in clathrin-mediated endocytosis of synaptic vesicles (SVs). All members of the BAR family share a highly conserved N-terminal BAR domain and a C-terminal Src homology (SH3) domain. Two isoforms of amphiphysin have been identified and act in concert as a heterodimer. Amphiphysins interact via its carboxy-terminal SH3 domain with dynamin, synaptojanin and clathrin. These complexes are implicated in synaptic vesicle recycling at nerve terminal. Amphiphysins were also identified as the dominant autoantigen in paraneoplastic Stiff-Man Syndrome.
Western Blot: 0.1ug/ml; Immunoprecipitation: 2.0ug; Immunohistochemistry: Paraffin-embedded sections; : 1:100; Immunocytochemistry: 1:100;
Type: Primary
Antigen: AMPH (amphiphysin)
Clonality: Monoclonal
Clone: C14-23
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1 Kappa
Reactivity: Mouse, Rat