AG-879
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AG-879
Supplier: Abcam
Selective TrkA receptor inhibitor. Inhibits NGF-dependent TrkA phosphorylation (IC₅₀ =40 μM). Additionally inhibits ErbB2 and the VEGF receptor FLK-1 (IC₅₀ =~1 μM). Active in vitroand in vivo. Shows antitumor activity.
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