Hai cercato: 4-(3-Pyridin-2-yl-1H-pyrazol-4-yl)quinoline
Sort By
4-(3-Pyridin-2-yl-1H-pyrazol-4-yl)quinoline 97%
Supplier: Apollo Scientific
4-(3-Pyridin-2-yl-1H-pyrazol-4-yl)quinoline 97%
Expand 1 Items
Caricamento...
4-(3-Pyridin-2-yl-1H-pyrazol-4-yl)quinoline ≥97% (by 1H-NMR)
Supplier: ENZO LIFE SCIENCES
Cell permeable, potent, selective and ATP-competitive inhibitor of TGF-β RI kinase (IC50=51nM). Displays ~15-fold greater selectivity over p38α MAPK (IC50=740nM). Inhibits TGF-β-dependent cellular growth (IC50=89nM in NIH 3T3 mouse fibroblasts) and transcription activation (IC50=47nM in mink lung cells). Suppresses invasion of MDA-MB-231 breast cancer cells in a matrigel invasion assay.
Expand 1 Items
Caricamento...
Sort By
Recommended for You