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(-)-Indolactam V

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(-)-Indolactam V ≥97%, solid

Supplier: Cayman Chemical

(−)-Indolactam V is a tumor-promoting teleocidin compound that activates protein kinase C (PKC). It binds to PKC regulatory domains of mouse skin PKCη and rat brain PKCγ with Ki values of 3,4 nM and 1 μM, respectively. At 1 μM, (−)-indolactam V induces differentiation of human embryonic stem cells into pancreatic progenitors through activation of PKC signaling.

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