Supplier: Tonbo Biosciences

The 145-2C11 antibody is specific for mouse CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can result in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.

Supplier: HONEYWELL SAFETY

The half mask MX/PF is designed to work when the type of protection depends on the cartridges connected, gases, particles or combined. The APF is evaluated from 12 to 50.

Supplier: Avantor Fluid Handling

Easy-to-use drives offer precise speed control and digital display of rpm—NEMA 4X housings stand up to process and washdown applications.

Supplier: Tonbo Biosciences

The 145-2C11 antibody is specific for mouse CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can result in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.

Supplier: Tonbo Biosciences

The 145-2C11 antibody is specific for mouse CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can result in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.

Supplier: Apollo Scientific

1H,1H,2H,2H-perfluorooctyltriethoxysilane (CAS 51851-37-7) is a flourinated alkyl silane. Apollo Scientific supplies 1H,1H,2H,2H-perfluorooctyltriethoxysilane to R&D, Academic institutions, and manufacturers across the UK and USA.

Supplier: Tonbo Biosciences

The 145-2C11 antibody is specific for mouse CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can result in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.

Supplier: MP Biomedicals

Vinblastine Sulphate is an anti-tumor alkaloid.

Supplier: 3M

Scotch-Brite™ Diamond floor brush 1000 series is designed to clean and polish uncoated concrete, terrazzo and potentially other stone floors in one step. Brush 1000 is a coarser grit brush intended for daily use on floors where low gloss is desired.

Supplier: MACHEREY-NAGEL

These screw neck vials are characterized by a wide opening and a short thread.

Supplier: ProSci Inc.

Nucleolin (NCL) is the major nucleolar phosphoprotein of growing eukaryotic cells. It is located mainly in dense fibrillar regions of the nucleolus. NCL is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly.

Supplier: ProSci Inc.

Involucrin is a highly reactive, soluble, transglutaminase substrate protein present in keratinocytes of epidermis and other stratified squamous epithelia. It first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase thus helping in the formation of an insoluble envelope beneath the plasma membrane functioning as a glutamyl donor during assembly of the cornified envelope. [Wiki].

Supplier: ProSci Inc.

4E-BP1 encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Supplier: ProSci Inc.

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Supplier: ProSci Inc.

NSF (N-ethylmaleimide sensitive fusion protein) is a critical component of the SNARE (soluble NSF attachment protein receptors) protein complex that is involved in synaptic vesicle trafficking. Specifically, NSF has been found to be essential in membrane fusion. Furthermore, NSF has been recently demonstrated to bind other protein complexes such as AMPA receptor subunits (GluR2), GATE-16, LMA-1 and Rabs suggesting a more diverse role in the assembly of various protein complexes (Whiteheart et al., 2004).

Supplier: UVEX

These cotton interlock safety gloves feature a special NBR coating on palm, fingers and ³/₄ of the back of the hand. Ideal for use in oily and greasy areas of application.

Supplier: DRUMMOND

The Pipet-Aid® was designed to transfer liquids with the use of serological, volumetric and/or blow-out pipettes in either glass, plastic or something similar. It accepts 1 to 100 ml pipettes.

Supplier: EP SCIENTIFIC

Type III soda-lime glass

Supplier: ProSci Inc.

MYST2 belongs to the MYST family, which is characterized by a highly conserved C2HC zinc finger and a putative histone acetyltransferase domain. MYST2 specifically represses AR-mediated transcription. MYST2 is a new AR-interacting protein capable of modulating AR activity. It could play a significant role in regulating AR-dependent genes in normal and prostate cancer cells. The biochemical and genetic interactions of MYST family protein MYST2 with two components of the replication apparatus, MCM2 and ORC1, suggest that MYST2-associated HAT activity may play a direct role in the process of DNA replication. MYST2 is a positive regulatory factor for prereplicative complex assembly.

Supplier: DESCO

The Desco Europe Slim Earth Bonding Point Bar (or Common Ground Point) has been designed to be installed underneath bench tops where it will be accessible to all connecting ground cords and where it is unlikely to be knocked and damaged or hinder the operator.

Supplier: JUSTRITE MANUFACTURING

High quality anti-fatigue matting for use in areas where there can be frequent oil spilling.

Supplier: Ansell

Dexterity with superb cut resistance for optimal productivity.

Supplier: Ansell

Mechanical protection gloves granting superior cut resistance and optimal comfort

Supplier: ProSci Inc.

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Supplier: ProSci Inc.

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Supplier: DWK Life Sciences

Glass, clear.

Supplier: HAMMERBACHER

Can be used individually, large variety of colours. Carcass construction, i.e. each rack can stand on its own.

Supplier: HAMMERBACHER

Can be used individually, large variety of colours. Carcass construction, i.e. each rack can stand on its own.

Supplier: Avantor Fluid Handling

Ultra-clean and reliable fittings for highly critical and corrosive chemicals.

Supplier: OMNIFIT

EZ SolventPlus™ columns are designed for maximum chemical compatibility. Borosilicate glass and PTFE construction, with Chemraz® o-rings and PTFE frits, only the most inert materials are present in the fluid path. ETFE end caps and fitting nuts ensure a chemically inert connection into and out of the system.