"Other Essentials"

Supplier: Trajan Scientific and Medical

Big Trap gas purifiers are designed for bulk purification applications, or where several instruments are plumbed from a single source.

Supplier: G-Biosciences

Detergents are essential for protein solubility during protein extraction and sample preparation, especially when working with hydrophobic proteins. The presence of high concentrations of detergents in protein samples can impair ELISA, IEF, protease digestion of proteins and suppress peptide ionisation when analysed by mass spectrometry.

Supplier: MP Biomedicals

Essential vitamin that is important for amino acid and energy metabolism, and fatty acid synthesis. It is a prosthetic group in four mammalian carboxylase families and facilitates the binding and transfer of carbon dioxide.

Supplier: Abcam

Anti-Desmin rabbit polyclonal Cytoskeleton Marker antibody that is designed to detect desmin, a muscle-specific type III intermediate filament essential for proper muscular structure and function. Used in Desmin IHC, ICC/IF. Suitable for Human, Mouse, Rat samples. - Trusted by researchers since 2004 - Top cited Desmin antibody with over 200 publications.

Supplier: Abcam

Abundant essential n-3 polyunsaturated fatty acid in the CNS, shown to play a major anti-inflammatory role. Prevents LPS-induced dendritic cell maturation, characterised by a lack of proinflammatory cytokine production. Improves the nitroso-redox balance and reduces VEGF-mediated angiogenic signaling in microvascular endothelial cells. Inhibits Aβ1-42 fibrillation and toxicity in vitro. Retinoid X receptor (RXR) ligand.

Supplier: Abcam

Anti-CLEC9A antibody [EPR24271-117] is a Rabbit Monoclonal antibody that is used in CLEC9A Flow Cytometry (Intra), IHC-P. Suitable for Mouse samples. C-type lectin domain containing 9A (Clec9a) is an endocytic receptor that recognizes danger signals exposed on necrotic cells. It's essential for the cross-presentation of dead cell-associated antigens, which is crucial for initiating innate immune responses.

Supplier: Abcam

Anti-PRDM1/Blimp1 antibody [EPR25163-80] is a Rabbit Monoclonal antibody that is used in PRDM1/Blimp1 IHC-P, IP, Western Blot. Suitable for Human samples. PRDM1(Blimp1) is a transcription factor that plays a crucial role in the differentiation of plasma cells and CD8+ effector T cells. It regulates the expression of genes involved in immune responses and is essential for the terminal differentiation and function of various immune cell.

Supplier: Abcam

Anti-KDM4B/JMJD2B antibody [EPR25240-51] is a Rabbit Monoclonal antibody that is used in KDM4B/JMJD2B IHC-P, Western Blot. Suitable for Human samples. KDM4B, also known as JMJD2B, is an enzyme that demethylates histone H3 at lysine 9 (H3K9), playing a pivotal role in altering the histone code. This enzyme is essential for chromatin remodeling and regulating gene expression, impacting critical processes like brain development and cancer progression.

Supplier: Abcam

Recombinant Human IKK gamma/NEMO protein is a Human Full Length protein, in the 1 to 419 aa range, expressed in Baculovirus infected Sf9, with =95% purity and suitable for SDS-PAGE, WB.

Supplier: Biomol Enzo

DegP acts as a chaperone at low temperatures but switches to a peptidase (heat shock protein) at higher temperatures. It degrades transiently denatured and unfolded proteins which accumulate in the periplasm following heat shock or other stress conditions.

Supplier: Biotium

MTS, TS and maleimide, and other thiol-modifying reagents and reactive fluorescent dyes.

Supplier: Abcam

Anti-DDX6 antibody [EPR27016-10] is a Rabbit Monoclonal antibody that is used in DDX6 ICC/IF, IHC-P, IP, Western Blot. Suitable for Human, Mouse, Rat samples. DDX6 is an RNA helicase involved in the regulation of mRNA metabolism, including translation suppression and mRNA degradation. It plays a crucial role in the formation of P-bodies and stress granules, which are essential for the storage and decay of mRNAs. Additionally, DDX6 is required for microRNA-induced gene silencing, impacting gene expression regulation.

Supplier: Abcam

Anti-Brd4 antibody [EPR29186-23] is a Rabbit Monoclonal antibody that is used in Brd4 Dot Blot, IHC-P, Western Blot. Suitable for Human, Mouse, Rat samples. BRD4 (Bromodomain-containing protein 4) is a chromatin reader protein that recognises and binds acetylated histones, playing a crucial role in transcription regulation. It is part of the BET (bromodomain and extra terminal domain) family, which includes BRD2, BRD3, and BRDT. BRD4 is involved in maintaining epigenetic memory across cell divisions and is essential for the expression of certain oncogenes in various cancers.

Supplier: Trajan Scientific and Medical

Gas purifiers are designed to provide fast stabilisation times to reduce gas consumption and provide clean gas to GC and GC/MS systems.

Supplier: Abcam

Anti-KMT2B/MLL4 C-terminal antibody [EPR27970-7] is a Rabbit Monoclonal antibody that is used in KMT2B/MLL4 ChIP-seq, Dot Blot, Western Blot. Suitable for Human, Mouse, Rat samples. KMT2B (MLL4) is a histone methyltransferase that specifically methylates histone H3 at lysine 4 (H3K4), playing a key role in gene regulation. It is involved in chromatin remodeling and is essential for the regulation of developmental genes and stem cell differentiation. Mutations in KMT2B have been linked to various cancers and developmental disorders.

Supplier: Abcam

Anti-Anti antibody [RP23040238] is a Rabbit Recombinant Multiclonal antibody that is used in Anti ICC/IF, Western Blot. Suitable for Human, Mouse samples. Liver arginase, particularly arginase-1 (ARG1), plays a significant role in cancer by regulating the proliferation, migration, and apoptosis of cancer cells. It contributes to immunosuppression and promotes the synthesis of polyamines, which are essential for tumor growth. Targeting arginase activity is being explored as a potential therapeutic strategy to inhibit cancer progression.