Human Recombinant Bc1-w (from E. coli)
N° de catalogue PRSI91-088
Fournisseur: ProSci Inc.
New Product
Numéro CAS:
Spécifications
- Cdt:0,05 mg
- Type de protéine/peptide:Recombinant
- Source:E. coli
- Species:Human
- Tag sequence:C-6 His tag
- Conditions de stockage:Store at −20 °C, stable for 6 months after receipt. Please minimise freeze-thaw cycles.
- Teneur en endotoxines:<0,1 ng/µg (1 IEU/µg) as determined by LAL test
- Synonyme de protéine:Bcl-2-like Protein 2|Bcl2-L-2|BCL2L2|Bcl-2-Llike Protein 2|Apoptosis Regulator Bcl-W|KIAA0271|BCLW
- Nom de la protéine/du peptide:Bc1-w
- Purity:>95% as determined by reducing SDS-PAGE
- Molecular weight:19,87 kDa
- Sequence:Ala2-Thr172
- Formulation:Supplied as a 0,2 µm filtered solution of 25 mM HEPES, 100 mM KCl, 20% Glycerol, pH 7,5. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the Lyophilised protein in ddH₂O. Please aliquot the reconstituted solution to minimise freeze-thaw cycles.
- Tested applications:Bioassay
Spécifications
À propos de cet article
Bcl-2-like protein 2 (BCL2L2) belongs to the Bcl-2 family. BCL2L2 is highly expressed in thebrain, spinal cord, testis, pancreas, heart, spleen, and mammary glands. BCL2L2 is a peripheral membrane protein containing three motifs, BH1, BH2 and BH4. The BH4 motif appears to be involved in the anti-apoptotic function. The BH1 and BH2 motifs form a hydrophobic groove which acts as a docking site for the BH3 domain of some pro-apoptotic proteins. BCL2L2 promotes cell survival and blocks dexamethasone-induced apoptosis. Furthermore, BCL2L2 mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX.
- Fusion-Tag: C-6 His tag
This recombinant protein can be used for biological assays.
Attention: For research use only.