1 mg

1 mg

Unconjugated

Recombinant

HEK293 cells

Cynomolgus monkey

–20 °C

Less than 1,0 EU per μg by the LAL method.

Lyophilised from 0,22 μm filtered solution in PBS, pH 7,4. Normally trehalose is added as protectant before lyophilisation.; Measured by its binding ability in a functional ELISA. Immobilised Rituximab at 5 μg/ml (100 μl/well) can bind Cynomolgus CD16, His Tag (BLI verified) with a linear range of 39-313 ng/ml (QC tested); Captured Cynomolgus CD16, His Tag (BLI verified)on CM5 chip via anti-His antibody can bind MabThera® (Rituximab) with an affinity constant of 0,206 μM as determined in a SPR assay (Biacore T200) (Routinely tested).; Loaded Cynomolgus CD16, His Tag (BLI verified) on HIS1K Biosensor, can bind Rituximab with an affinity constant of 0,287 μM as determined in BLI assay (ForteBio Octet Red96e) (QC tested).; Loaded Herceptin on Protein A Biosensor, can bind Cynomolgus CD16, His Tag (BLI verified) with an affinity constant of 0,31 μM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).; Loaded Herceptin on FAB2G Biosensor, can bind Cynomolgus CD16, His Tag (BLI verified) with an affinity constant of 0,23 μM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested)

Q8SPW2-1

Y

Y

Y

FCGR3

Fc gamma RIII / CD16

>95%

23,8 kDa

Low

Lyophilised from 0,22 μm filtered solution in PBS, pH 7,4. Normally trehalose is added as protectant before lyophilisation

Y

Powder,RT