In vivo DogtorMag™ transfection reagent has been designed for in vivo targeted transfection of various types of nucleic acids, such as DNA, RNA, oligonucleotides, using magnetic nanoparticles coated with synthetic lipids. DNA complexes can be easily administrated through various injection routes, such as systemic administration (intravenous, intra-artery) or local administration (intratumoral, intracerebroventricular).

• Increased transfection efficiency
• Targeted process (magnetically-driven)
• Reduction of the systemic dissemination of vectors during injection
• Reduction of the vector doses
• Work under non permissive conditions (hypothermia, physiological flow conditions)
• Penetration of the vector into tissues
• Minimized toxicity
• Universal – suitable for all nucleic acids

In vivo DogtorMag™ kit contains in vivo Dogtor transfection reagent plus in vivo CombiMag transfection reagent.

Store in vivo DogtorMag™ at –20 °C and in vivo CombiMag at +4 °C