tri-Sodium citrate dihydraté ≥99.0%, soluble, EMPROVE® ESSENTIAL Ph. Eur., JP, USP, E331, BP suitable for use as excipient, SAFC®

: MERCK PRODUCTION CHEMICALS

tri-Sodium citrate dihydraté ≥99.0%, soluble, EMPROVE® ESSENTIAL Ph. Eur., JP, USP, E331, BP suitable for use as excipient, SAFC®

: MERCK PRODUCTION CHEMICALS

: Sodium Citrate Dihydrate, Sodium citrate tribasic dihydrate, Sodium Citrate, Dihydrate, Sodium 2-hydroxypropane-1,2,3-tricarboxylate dihydrate, Citric acid trisodium salt dihydrate

:6132-04-3

:Na₃C₆H₅O₇·2H₂O

:MFCD00150031

:294.1 g/mol

:13,08675

:150 °C (anhydr.)

:1,76 g/cm³ (20 °C)

:Température ambiante

:200-675-3

Environmentally Preferable:

Assay (Perchloric acid titration, calc. on anhydrous substance (Ph Eur)):
99.0 - 101.0 %
Assay (Perchloric acid titration, previously dried substance) (JP/USP):
99.0 - 100.5 %
Identity (Na):
passes test
Identity (Citrate):
passes test
Identity (reaction upon ignition):
passes test
Appearance:
white to almost white crystals
Appearance of solution (100 g/l, CO₂-free water):
clear and colorless
Acidity or alkalinity:
passes test
pH (50 g/l CO₂-free water):
7.5 - 8.5
Chloride (Cl):
≤ 50 ppm
Sulfate (SO₄):
≤ 150 ppm
Heavy metals (as Pb):
≤ 5 ppm
Al (Aluminium):
≤ 5 ppm
As (Arsenic):
≤ 1 ppm
Hg (Mercury):
≤ 1 ppm
Pb (Lead):
≤ 1 ppm
Oxalate (as C₂H₂O₄):
≤ 100 ppm
Tartrate (C₄H₄O₆):
passes test
Residual solvents (ICH (Q3C)):
excluded by manufacturing process
Readily carbonisable substance:
passes test
Water (according to Karl Fischer):
11.0 - 13.0 %
Loss on drying (180 °C, 18 h):
10.0 - 13.0 %