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Mouse recombinant MegaCD40L™ (soluble) (from CHO cells)
Mouse recombinant MegaCD40L™ (soluble) (from CHO cells)
Catalog # ENZOALX522120C010
Supplier:  ENZO LIFE SCIENCES
CAS Number:  
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Mouse recombinant MegaCD40L™ (soluble) (from CHO cells)
Catalog # ENZOALX522120C010
Supplier:  ENZO LIFE SCIENCES
CAS Number:  

Specifications

  • Cdt:
    10 µG
  • Type de protéine/peptide:
    Recombinant
  • Source:
    CHO cells
  • Species:
    Mouse
  • Seq:
    02
  • Activité biologique:
    Binds to mouse and human CD40. Induces B cells activation (as demonstrated by dose-dependent upregulation of CD86).
  • Reconstitution instructions:
    Reconstitute with 100 µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum.
  • Nom de la protéine/du peptide:
    MegaCD40L™ (soluble)
  • Purity:
    >95% (SDS-PAGE)
  • Concentration:
    0,1 mg/ml after reconstitution
  • Formulation:
    Lyophilised. Contains PBS.

Specifications

About this item

Highly active

Produced in CHO cells. The extracellular domain of mouse CD40L (CD154) (aa 115-260) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG®-tag.

MegaCD40L™ is a high activity construct in which two trimeric CD40 ligands are artificially linked via the collagen domain of ACRP30/adiponectin. This construct very effectively simulates the natural membrane-assisted aggregation of CD40L. It provides a simple and equally potent alternative to [CD40L+enhancer] combinations (Prod. No. ALX-850-075).