Mouse recombinant MegaCD40L™ (soluble) (from CHO cells)
Catalog # ENZOALX522120C010
Supplier: ENZO LIFE SCIENCES
CAS Number:
Specifications
- Cdt:10 µG
- Type de protéine/peptide:Recombinant
- Source:CHO cells
- Species:Mouse
- Seq:02
- Activité biologique:Binds to mouse and human CD40. Induces B cells activation (as demonstrated by dose-dependent upregulation of CD86).
- Reconstitution instructions:Reconstitute with 100 µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum.
- Nom de la protéine/du peptide:MegaCD40L™ (soluble)
- Purity:>95% (SDS-PAGE)
- Concentration:0,1 mg/ml after reconstitution
- Formulation:Lyophilised. Contains PBS.
Specifications
About this item
Highly active
Produced in CHO cells. The extracellular domain of mouse CD40L (CD154) (aa 115-260) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG®-tag.
MegaCD40L™ is a high activity construct in which two trimeric CD40 ligands are artificially linked via the collagen domain of ACRP30/adiponectin. This construct very effectively simulates the natural membrane-assisted aggregation of CD40L. It provides a simple and equally potent alternative to [CD40L+enhancer] combinations (Prod. No. ALX-850-075).