Technische Daten
- Type d'anticorps:Primaire
- Nom de l'antigène:Ca++-dependent Secretion Activator 2
- Symbole de l'antigène:CADPS2
- Clonalité:Polyclonal
- Conjugaison:Cy3®
- Hôte:Rabbit
- ImmunoChimie:Yes
- Isotype:IgG
- Réactivité:Human,Rat,Mouse
- Adsorption croisée:No
- Formulaire:liquid
- Synonymes antigène:KIAA1591|CAPS2|Calcium-dependent secretion activator 2|CAPS-2|Calcium-dependent activator protein for secretion 2
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Température de stockage:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Température de transport:4°C
- Purification:Purified by Protein A
- Cdt:100 µl
Technische Daten
Über diesen Artikel
Calcium-dependent secretion activators (CAPS-1 and CAPS-2) are calcium-binding proteins that direct neurotransmitter and neuropeptide-filled vesicles to the cell membrane for secretory granule exocytosis. Both CAPS-1 and CAPS-2 are expressed primarily in the brain where they regulate the secretion of various substances. The CAPS proteins contain a PH domain that is essential for regulation of exocytosis, as well as regulation of phospholipid binding. Through their regulation of neurotrophin release from granule cells, CAPS proteins help to regulate cell fate during neuronal development. CAPS-1 is thought to regulate catecholamine release from neuronal cells, while CAPS-2 is thought to regulate release of both brain-derived neurotrophic factor and neurotrophin-3 from granule cells. Defects in the genes encoding CAPS-1 and CAPS-2 are implicated in impaired cerebral development and autism.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: CADPS2
Clonality: Polyclonal
Clone:
Conjugation: Cy3®
Epitope:
Host: Rabbit
Isotype: IgG1
Reactivity: Human, Mouse, Rat