Human PTX3 ELISA Kit for the quantitative detection of human pentraxin 3.

• No detectable cross-reactivity with other relevant proteins

Pentraxin 3 is a member of the pentraxin superfamily. This super family is characterised by cyclic multimeric structure. The PTX3 gene is mapped to 3q25.32. The predicted 381-amino acid PTX3 protein has homology to the pentraxin protein family. Significant levels of PTX3 were detected in plasma of neutropenic patients with systemic A. PTX3 is effective in preventing CMV infection and reactivation, as well as subsequent Aspergillus infection. PTX3 activates the classical pathway of complement activation and facilitates pathogen recognition by macrophages and DCs.