PlasmidSelect Xtra is a thiophilic aromatic adsorption chromatography medium with a selectivity that allows generic purification of supercoiled covalently closed circular forms of plasmid DNA to be separated from open circular forms.

• Allows for generic purification of supercoiled plasmid DNA
• Allows for consistent purification results when scaling up from research scale to cGMP production
• Hydrophilic nature of the base matrix ensures low levels of non specific binding
• BioProcess medium supported for industrial applications

Available in convenient prepacked format for research, process development and quantitative and qualitative analysis of supercoiled plasmid DNA.

Degree of substitution: Approx. 3,5 mg 2-mercaptopyridine/ml medium
Pressure/flow specification: <120 cm/h, XK 16/20 column, bed height 15 cm
Storage conditions: 4 to 30 °C, 20% ethanol
Chemical stability: stable in commonly used aqueous buffers