Organic synthesis with Thermo Scientific chemicals
Explore our reagents and materials for synthesis and study of reaction mechanisms, including air- and moisture-sensitive reagents and building blocks.
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The most commonly used functional reagents, plus more unusual reagents for specific reactions.
Heterocyclic compounds are cyclic compounds containing atoms least two different elements in the ring, and include nitrogen, oxygen, sulphur and mixed heterocycles.
Hydrocarbons are organic compounds made up entirely of carbon and hydrogen atoms.
Inorganics include salts, metals, and substances made from single elements. In general, they are ionic compounds consisting of cations and anions joined by ionic bonding.
Organohalides are organic compounds containing fluorine, chlorine, bromine, and iodine.
Nitrogen-containing compounds include, among others, amines and derivatives, nitriles, azides, and hydrazines.
Oxygen-containing compounds include alcohols, aldehydes, ketones and ethers, also carboxylic acids and derivatives.
Phosphorus-containing compounds include esters of organophosphorus acids, phosphonic esters, phosphines, and phosphites.
Sulfur-containing compounds include thiols, thioethers, thioesters, thioureas, sulfonamides, and sulfoxides.
Organic polymers include polysaccharides, polypeptides, polynucleotides, and synthetic materials such as the common plastics, e.g., polyethylene, polyvinylchloride, and polystyrene.
Chemical compounds containing at least one chemical bond between a carbon atom of an organic molecule and a metal, including alkaline, alkaline earth, and transition metals, and sometimes broadened to include metalloids like boron, silicon and selenium.
Biochemical refer to any chemical that is found in a biological system or that can be used for biological research. Biochemical compounds include molecules such as amino acids, vitamins, and nucleotides as well as organic and inorganic chemicals.
Additional information
These are substances, (usually inorganic compounds or small organic molecules), used in the synthesis of organic compounds.
Learn more on Wolff Kishner Reduction which explains the reduction of aldehydes and ketones to alkanes.
Discover the Wittig Reaction allowing the preparation of an alkene by the reaction of an aldehyde or ketone with the ylide generated from a phosphonium salt.
Know more on the Fischer Indole Synthesis which explains the conversion of aryl hydrazones to indoles
Learn more on the Wohl Ziegler Bromination which is the bromination of allylic positions with N-bromosuccinimide (NBS).
Know more on the Simmons Smith Reaction affording the cyclopropanation of olefins.
Discover the Clemmensen Reduction allowing the deoxygenation of aldehydes or ketones, to produce the corresponding hydrocarbon
Suzuki Cross coupling Reaction is a metal catalyzed reaction, typically with Pd, between an alkenyl (vinyl), aryl, or alkynyl organoborane (boronic acid or boronic ester, or special cases with aryl trifluoroborane) and halide or triflate under basic conditions.
Discover the Friedel–Crafts acylation which is the reaction of an arene with acyl chlorides or anhydrides using a strong Lewis acid catalyst.
Learn more the Baeyer-Villiger Oxidation is the oxidative cleavage of a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters and cyclic ketones to lactones
Discover the Beckmann rearrangement Reaction which is a reaction of oximes that can result in either amides or nitriles, depending on the starting material. (Oximes derived from ketones give amides; oximes derived from aldehydes provide nitriles)
Know more on the Grignard Reaction which is the addition of an organo-magnesium halide (Grignard reagent) to a ketone or aldehyde, to form a tertiary or secondary alcohol, respectively
Watch and know more on the Dess-Martin Periodinane (DMP), a hypervalent iodine compound, offering selective and very mild oxidation of alcohols to aldehydes or ketones.