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Supplier: US Biological

Anti-AK3 Mouse Polyclonal Antibody

Supplier: US Biological

Anti-AK2 Rabbit Polyclonal Antibody (Biotin)

Supplier: US Biological

Anti-AK2 Rabbit Polyclonal Antibody (Biotin)

Supplier: US Biological

Anti-CREB1 Mouse Monoclonal Antibody [clone: 3F1-1B2]

Supplier: Thermo Fisher Scientific

Adenosine-3',5'-cyclic monophosphate sodium salt 99%

Supplier: US Biological

Anti-PDE11A Goat Polyclonal Antibody

Supplier: US Biological

Anti-AK3 Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-PRKAA1 Mouse Polyclonal Antibody

Supplier: US Biological

Anti-ATF1 Rabbit Polyclonal Antibody (Biotin)

Supplier: Thermo Fisher Scientific

2-Acrylamido-2-methylpropanesulphonic acid ≥98%

Supplier: Merck

The kit contains a set of nine brown colour reference standards (identified sequentially from B1 to B9) and a 1% hydrogen chloride solution in water. The solutions are produced from three primary metal salt solutions of ferric(III) chloride, cobalt(II) chloride, and copper(II) sulfate pentahydrate, in accordance with chapter 2.2.2 ′Degree of colouration of liquids′ of the European Pharmacopoeia (Ph. Eur.).

Supplier: US Biological

Anti-AK4 Rabbit Polyclonal Antibody

Supplier: OriGene

Anti-IgG (H+L) Goat Antibody (HRP (Horseradish Peroxidase))

Supplier: US Biological

Anti-PRKAA1 Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-CREB5 Rabbit Polyclonal Antibody

Supplier: Bioss

AMPK is a heterotrimeric complex comprising a catalytic a subunit and regulatory b and g subunits. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is activated by high AMP and low ATP through a mechanism involving allosteric regulation, promotion of phosphorylation by an upstream protein kinase known as AMPK kinase and inhibition of dephosphorylation. Activated AMPK can phosphorylate and regulate in vivo hydroxy-methylglutaryl-CoA reductase and acetyl-CoA carboxylase, which are key regulatory enzymes of sterol synthesis and fatty acid synthesis, respectively. The human AMPKa1 and AMPKa2 genes encode 548 amino acid and 552 amino acid proteins, respectively. Human AMPKb1 encodes a 271 amino acid protein and human AMPKb2 encodes a 272 amino acid protein. The human AMPKg1 gene encodes a 331 amino acid protein. Human AMPKg2 and AMPKg3, which are 569 and 492 amino acid proteins, respectively, contain unique N-terminal domains and may participate directly in the binding of AMP within the AMPK complex.