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2189 results for "TMC HALLCREST"

2189 Results for: "TMC HALLCREST"

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Monastrol ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Cell permeable non-tubulin-interacting mitosis inhibitor. Blocks mitosis (IC50=14µM) by binding to the mitotic kinesin Eg5.

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2',5'-Dideoxyadenosine ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Adenylate cyclase inhibitor

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4-Hydroxybenzylidenemalononitrile ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

The tyrphostins are well known tyrosine kinase inhibitors. However, tyrphostin 8 has been shown to inhibit calcineurin (IC50=21 µM) while displaying weak inhibition of EGFR tyrosine kinase (IC50=560 µM).

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FH535 ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Inhibits the recruitment of the co-activators β-catenin and GRIP1

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Dorsomorphin ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Cell-permeable pyrrazolopyrimidine derivative that inhibits AMP kinase (Ki=109nM in the absence of AMP) in an ATP-competitive manner. It displays no significant inhibition of ZAPK, SYK, PKCT, PKA and JAK3. Decreases food intake in mice and inhibits the effects of AICAR and metformin. It has been shown to inhibit BMP type I receptors ALK2, ALK3 and ALK6. Promotes cardiomyogenesis in mouse embryonic stem cells. Induces protective autophagy in cancer cell lines.

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Icilin ≥97% (by TLC)

Supplier: ENZO LIFE SCIENCES

TRPM8 activator.

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N-Arachidonoyldopamine ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Activator of CB1 receptor and TRPV1

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DICA ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Inhibitor of caspase-3 and caspase-7 binding to an allosteric site and not to the active site.

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(S)-Mephenytoin ≥98% (by TLC)

(S)-Mephenytoin ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Cytochrome P450 substrate.

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(+/-)-Anatoxin ≥98% (by TLC)

(+/-)-Anatoxin ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Nicotinic acetylcholine receptor ligand.

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STAT3 Inhibitor V, Stattic ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Small molecule STAT3-specific inhibitor which blocks activation, dimerization and nuclear translocation via binding to the STAT3 SH2 domain. It is a very useful tool for exploring STAT3-mediated signaling pathways. It blocks LPS-mediated STAT3 tyrosine phosphorylation which leads to inhibition of LPS-mediated IL-1β and IL-6 production. In primary cultures of rat neural stem cells it blocks IL-15-induced differentiation.

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Troglitazone ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

PPAR ligand

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Ac-IETD-AMC

Supplier: ENZO LIFE SCIENCES

Caspase and granzyme substrate

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Pravadoline ≥98% (by TLC)

Pravadoline ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Cannabinoid receptor agonist.

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Wedelolactone ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

IKK inhibitor

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ITSA-1 ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

HDAC inhibitor

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Calphostin C ≥99% (by TLC)

Supplier: ENZO LIFE SCIENCES

PKC inhibitor

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Necrostatin-1 ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Inhibits necroptosis

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KT5720 ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

PKA inhibitor

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Ac-VEID-AMC

Supplier: ENZO LIFE SCIENCES

Caspase-6 substrate

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Cycloheximide ≥95% (by TLC)

Supplier: ENZO LIFE SCIENCES

Protein synthesis inhibitor

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AUDA ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Novel inhibitor of soluble epoxide hydrolase (IC50=18nM and 69nM for the mouse and human enzymes respectively). Produces a hypotensive effect in angiotensin-infused rats and prevents and reverses cardiac hypertrophy in mouse models of cardiac hypertrophy.

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IDE 2 ≥98% (by TLC)

IDE 2 ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Induces stem cell differentiation.

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NOB ≥98% (by TLC)

NOB ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

PLA₂ substrate

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Resveratrol ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Antioxidant. SIRT1 activator.

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T0901317 ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

LXR activator

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NNGH ≥99% (by TLC)

Supplier: ENZO LIFE SCIENCES

MMP inhibitor

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TCPOBOP ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Constitutive androstane receptor (CAR) activator.

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Ellipticine ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

A DNA-intercalating antitumor agent. Inhibits DNA topoisomerase II. Inhibits the phosphorylation of p53 in Lewis lung carcinoma cells and induces apoptosis. Inhibits cytochrome P-450-1A1.

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SBHA ≥95% (by TLC)

Supplier: ENZO LIFE SCIENCES

Induces cellular differentiation. Inhibits histone deacetylation.

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