138 Results for: "Respiratory Protection"

Supplier: ProSci Inc.

Lipocalin-2, also known as Neutrophil Gelatinase-Associated Lipocalin (NGAL), is a secretory protein of the lipocalin superfamily. Lipocalin-2 contains a signal peptide that enables it to be secreted and form complexes with matrix metalloproteinase-9 (MMP-9) through disulphide bonds. Similar to other lipocalin family members, Lipocalin-2 is involved in diverse cellular processes, including the transport of small hydrophobic molecules, protection of MMP-9 from proteolytic degradation, and cell signalling. Furthermore, Lipocalin-2 can tightly bind to bacterial siderophore through a cell surface receptor, possibly serving as a potent bacteriostatic agent by sequestering iron, regulating innate immunity and protecting kidney epithelial cells from ischemia–reperfusion injury. This protein is mainly expressed in neutrophils and in lower levels in the kidney, prostate, and epithelia of the respiratory and alimentary tracts. Recent evidence also suggests its role as a biomarker for renal injury and inflammation.

Supplier: ProSci Inc.

Lipocalin-2, also known as Neutrophil Gelatinase-Associated Lipocalin (NGAL), is a secretory protein of the lipocalin superfamily. Lipocalin-2 contains a signal peptide that enables it to be secreted and form complexes with matrix metalloproteinase-9 (MMP-9) through disulphide bonds. Similar to other lipocalin family members, Lipocalin-2 is involved in diverse cellular processes, including the transport of small hydrophobic molecules, protection of MMP-9 from proteolytic degradation, and cell signalling. Furthermore, Lipocalin-2 can tightly bind to bacterial siderophore through a cell surface receptor, possibly serving as a potent bacteriostatic agent by sequestering iron, regulating innate immunity and protecting kidney epithelial cells from ischemia–reperfusion injury. This protein is mainly expressed in neutrophils and in lower levels in the kidney, prostate, and epithelia of the respiratory and alimentary tracts. Recent evidence also suggests its role as a biomarker for renal injury and inflammation.

Supplier: AbFrontier

α1-antitrypsin, 52kDa, is the prototypic member of the serine protease inhibitor (serpin) superfamily, which have a major role in inactivating neutrophil elastase and other proteases to maintain protease-antiprotease balance. The protein is synthesized mainly in the liver, but exerts its main function in the lung where it inhibits a variety of serine proteases, but primarily neutrophil elastase. It provides more than 90% of the antiproteolytic shield of the lower respiratory tract protecting the elastic tissue from degradation. Disorders of the enzyme include α 1-antitrypsin deficiency, a hereditary disorder in which lack of α 1-antitrypsin leads to uninhibited tissue breakdown during inflammation. This causes pulmonary emphysema and leads to liver cirrhosis in severe cases.

Supplier: Dräger

The X-plore® 1700 series offers models in all three EN protection classes: FFP1, FFP2, and FFP3. Available with or without CoolMax™ exhalation valve for reduced exhalation resistance and to avoid a build-up of heat. Odour models for tackling unpleasant odours are equipped with an additional activated carbon layer.

Supplier: UVEX

The Uvex silv-Air premium product line comprises classic, white folding respirators that adapt to different face shapes. The headband and integrated sealing lip in all protection classes mean the masks are easy to put on correctly as well as making them comfortable to wear, even for extended periods.

Supplier: 3M

The Versaflo™ Cleaning and Storage Kit TR-653 is designed to assist with safely cleaning and storing the Versaflo™ Powered Air Turbo TR-600 and TR-800 Series. It comes with one inlet plug and two inlet seals, one outlet plug and two outlet seals, and one battery connector cover.

Supplier: Dräger

X-plore® 5500 full face masks offer the perfect solution wherever your work requires respiratory protection, e.g. in the chemical industry, metalworking and automotive industries, shipbuilding, maintenance, supply and disposal logistics. The double layered face seal with triple sealing action provides reliable protection and a tight fit for all face shapes and sizes. The large visor is available in two different materials: polycarbonate or triplex (excellent anti-scratch coating and high chemical-resistance).

Supplier: ProSci Inc.

Interleukin-22(IL-22) is a member of a group of the IL-10 family, a class of potent mediators of cellular inflammatory responses. IL-22 is produced by activated DC and T cells. IL-22 and IL-10 receptor chains play a role in cellular targeting and signal transduction. It can initiate and regulate innate immune responses against bacterial pathogens especially in epithelial cells such as respiratory and gut epithelial cells. IL-22 along with IL-17 likely plays a role in the coordinated response of both adaptive and innate immune systems. IL-22 also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10. Biological activity of IL-22 is initiated by binding to a cell-surface complex consisting of IL-22R1 and IL-10R2 receptor chains. IL-22 biological activity is further regulated by interactions with a soluble binding protein, IL-22BP. IL-22BP and an extracellular region of IL-22R1 share sequence similarity. In some cases, the pro-inflammatory versus tissue-protective functions of IL-22 are regulated by cytokine IL-17A.

Supplier: ProSci Inc.

Alpha-1 Antitrypsin or alpha1-antitrypsin (A1AT) is a protease inhibitor belonging to the serpin superfamily. It is generally known as serum trypsin inhibitor. Alpha 1-antitrypsin is also referred to as alpha-1 proteinase inhibitor (A1PI) because it inhibits a wide variety of proteases. It protects tissues from enzymes of inflammatory cells, especially neutrophil elastase, and has a reference range in blood of 1.5 - 3.5 gram/liter (in US the reference range is generally expressed as mg/dL or micromoles), but the concentration can rise manyfold upon acute inflammation. In its absence (such as in alpha 1-antitrypsin deficiency), neutrophil elastase is free to break down elastin, which contributes to the elasticity of the lungs, resulting in respiratory complications such as emphysema, or COPD (chronic obstructive pulmonary disease) in adults and cirrhosis in adults or children.

Like all serine protease inhibitors, A1AT has a characteristic secondary structure of beta sheets and alpha helices. Mutations in these areas can lead to non-functional proteins that can polymerise and accumulate in the liver (infantile hepatic cirrhosis). [Wiki].

Supplier: ProSci Inc.

Interleukin-22(IL-22) is a member of a group of the IL-10 family, a class of potent mediators of cellular inflammatory responses. IL-22 is produced by activated DC and T cells. IL-22 and IL-10 receptor chains play a role in cellular targeting and signal transduction. It can initiate and regulate innate immune responses against bacterial pathogens especially in epithelial cells such as respiratory and gut epithelial cells. IL-22 along with IL-17 likely plays a role in the coordinated response of both adaptive and innate immune systems. IL-22 also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10. Biological activity of IL-22 is initiated by binding to a cell-surface complex consisting of IL-22R1 and IL-10R2 receptor chains. IL-22 biological activity is further regulated by interactions with a soluble binding protein, IL-22BP. IL-22BP and an extracellular region of IL-22R1 share sequence similarity. In some cases, the pro-inflammatory versus tissue-protective functions of IL-22 are regulated by cytokine IL-17A.

Supplier: ProSci Inc.

Interleukin-22(IL-22) is a member of a group of the IL-10 family, a class of potent mediators of cellular inflammatory responses. IL-22 is produced by activated DC and T cells. IL-22 and IL-10 receptor chains play a role in cellular targeting and signal transduction. It can initiate and regulate innate immune responses against bacterial pathogens especially in epithelial cells such as respiratory and gut epithelial cells. IL-22 along with IL-17 likely plays a role in the coordinated response of both adaptive and innate immune systems. IL-22 also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10. Biological activity of IL-22 is initiated by binding to a cell-surface complex consisting of IL-22R1 and IL-10R2 receptor chains. IL-22 biological activity is further regulated by interactions with a soluble binding protein, IL-22BP. IL-22BP and an extracellular region of IL-22R1 share sequence similarity. In some cases, the pro-inflammatory versus tissue-protective functions of IL-22 are regulated by cytokine IL-17A.

Supplier: 3M

The Versaflo™ Forehead Seal M-154 is a replacement forehead seal designed for use with 3M™ Versaflo™ M-100 and M-200 Series Headtops.

Supplier: MP Biomedicals

Storage: +4 °C
Pyruvic acid is an intermediate in sugar metabolism and in enzymatic carbohydrate degradation (alcoholic fermentation) where it is converted to acetaldehyde and CO2 by carboxylase. In muscle, pyruvic acid (derived from glycogen) is reduced to lactic acid during exertion, which is reoxidized and partially retransformed to glycogen during rest. It improves coliform recovery when present in culture medium. It is involved in a metabolic regulatory pathway activated by mitochondrial oxidants. Pyruvate is involved in respiratory regulation in plants by interacting with alternative oxidase at a conserved cysteine residue. It may help prevent hydrogen peroxide mediated cell death.
Sodium pyruvate is utilized as a component in culture broth and media. Sodium pyruvate is used in Wallen fermentation medium to enhance the conversion of oleic acid to 10-ketostearic acid by Bacillus sphaericus. Sodium pyruvate has also been used to establish stably transfected human B cell lines.
Sodium Pyruvate has shown antioxidant properties and protective effects against oxygen radicals. Pyruvate is produced as part of glycolysis and is an intermediate in many metabolic pathways. It can be converted into acetyl CoA and enter the TCA Cycle.

Supplier: Portwest

Vertical flat folded mask with exhalation valve for lighter breathing resistance. Ideal for all day use.

Supplier: Bollé Safety

These goggles offer an outstanding field of vision, fit over prescription spectacles and can be worn with respiratory half masks. They offer unbeatable comfort and essential modular design. In combination with the accessory visor, this model can also be used as a face shield.

Supplier: 3M

Faceshield cover for improved lens protection, For: 3M™ Full Facepiece Respirators 6000 Series

Supplier: Honeywell Safety

Filter cartridge class P3, material: ABS - fiber glass paper, protection type: particulate

Supplier: 3M

These mask filters are light, comfortable and provide reliable protection from particulates. When using with 3M™ 6000 series masks, a 3M™ 502 adapter is required.

Supplier: 3M

The 3M 6000 Series Gas, Vapor, and Particulate Combination Filters have a bayonet-style connection that fits any half and full-face 3M reusable masks. These lightweight filters offer well-balanced breathing protection for hazardous environments, and are designed to optimise the field of vision.

Supplier: 3M

Test kits and accessories designed to help your organisation meet OSHA fit testing requirements for respirators. The products can be used to check face-to-respirator seal on any particulate respirator or gas/vapour respirator with a particulate prefilter. FT-10 uses a test solution of sodium saccharin that produces a sweet tasting aerosol.

Supplier: Roth Carl

Sekuroka-respiratory protection filters 1 * 1 items

Supplier: Roth Carl

Sekuroka-respiratory protection filters 1 * 1 items

Supplier: Roth Carl

Sekuroka-respiratory protection filters 1 * 1 items

Supplier: Roth Carl

Sekuroka-respiratory protection filters 1 * 1 items

Supplier: Roth Carl

Sekuroka-respiratory protection filters 1 * 1 items

Supplier: Dräger

BALL BLOWER DRAGER ACCESSORY FOR RESPIRATORY PROTECTION 1 * 1 items

Supplier: Medicom

Cat III EN149 FFP2 respiratory mask - duckbill - white 1 * 500 items

Supplier: Brady

Ensures individual usage and makes a valuable contribution to general safety signage.

Supplier: JSP

A range of polypropylene moulded disposable respirators, available in valved and unvalved options, offering a cost effective solution.

Supplier: JSP

Vertical fold flat respirator with foam padded adjustable nose clip and extended chin coverage.