58716 Results for: "Cayman Chemical"

Supplier: Cayman Chemical

BSA-Palmitate saturated fatty acid complex is composed of palmitic acid and bovine serum albumin (BSA) at an approximately 6:1 molar ratio of palmitate:BSA. It can be used for efficient fatty acid delivery to cells in culture for the purpose of monitoring fatty acid oxidation or similar processes in various cellular metabolic studies.

Supplier: Cayman Chemical

Hygromycin B

Supplier: Cayman Chemical

Doxorubicin is an anthracycline anti-tumour antibiotic which involves in inhibition of DNA topoisomerase II by inducing double-stranded DNA breaks. It is also involved in the inhibition of nucleic acid synthesis by intercalating within DNA. The accumulation of the p53 tumour suppressor protein leads to the apoptosis in cells.

Supplier: Cayman Chemical

Purvalanol A is a potent, cell-permeable, and selective inhibitor of cyclin-dependent kinases (CDKs) with IC50 values of 4, 70, 35, 850, and 75 nM for cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk4/cyclin D1 and Cdk5-p35, respectively.

Supplier: Cayman Chemical

CNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively, versus IC50 = 25 μM for NMDA receptors).
This compound has been used to specifically target AMPA and kainate receptor responses and thus differentiate from that of NMDA receptors.

Supplier: Cayman Chemical

N-Octyl-β-D-glucopyranoside

Supplier: Cayman Chemical

Probenecid

Supplier: Cayman Chemical

Neomycin sulphate

Supplier: Cayman Chemical

5-Fluoro-2'-deoxyuridine (floxuridine)

Supplier: Cayman Chemical

Dihydroethidium is a cell-permeable blue fluorescent dye that upon entering cells interacts with superoxide to form oxyethidium, which intercalates with nucleic acids and emits a red fluorescence detectable qualitatively by fluorescent microscopy or quantitatively by HPLC.

Supplier: Cayman Chemical

Thioisonicotinamide

Supplier: Cayman Chemical

4-Methyl-2-(2-pyridinyl)-5-thiazolecarboxylic acid

Supplier: Cayman Chemical

Leukotoxin is the 9(10) epoxide of linoleic acid, generated by neutrophils during the oxidative burst. This unstable compound is rapidly degraded by epoxide hydrolases to form the diol, (±)9(10)-DiHOME. Mitochondrial dysfunction, vasodilation and apoptosis are features of leukotoxin toxicity. In renal phydrolysesroximal tubular cells, the diol hydrolysis products of leukotoxin, such as (±)9(10)-DiHOME, have been directly implicated as the cytotoxic agent responsible for cell death.

Supplier: Cayman Chemical

Gallic acid

Supplier: Cayman Chemical

5-Fluorouracil

Supplier: Cayman Chemical

Anti-GPR12 Rabbit Polyclonal Antibody

Supplier: Cayman Chemical

γ-Linolenic acid methyl ester

Supplier: Cayman Chemical

Estrone

Supplier: Cayman Chemical

Anti-CB1 Rabbit Polyclonal Antibody

Supplier: Cayman Chemical

10-Acetyl-3,7-dihydroxyphenoxazine (ADHP) is a highly sensitive, stable substrate for horseradish peroxidase (HRP) that enables selective detection of H₂O₂.

Supplier: Cayman Chemical

Anti-11-beta-HSD1 Rabbit Polyclonal Antibody

Supplier: Cayman Chemical

Anti-BLT1 Mouse Monoclonal Antibody [clone: 7B1]

Supplier: Cayman Chemical

Anti-Vtg Mouse Monoclonal Antibody [clone: CK-1H11]

Supplier: Cayman Chemical

Anti-Zrp Mouse Monoclonal Antibody [clone: MN-2B4]

Supplier: Cayman Chemical

Linoleic acid-d4 contains four deuterium atoms at the 9, 10, 12, and 13 positions. It is intended for use as an internal standard for the quantification of linoleic acid by GC- or LC-mass spectrometry. Linoleic acid is a PUFA found in plant tissues and most cooking oils.

Supplier: Cayman Chemical

Phytanic acid is a saturated 20-carbon branched-chain fatty acid which can only be derived from dietary sources. In cases of peroxisomal disorders, elevated levels of phytanic acid are observed, and this is linked to diseases such as infantile phytanic acid storage disease and Refsum’s disease.

Supplier: Cayman Chemical

Cytochrome P450 (CYP450) enzymes are a superfamily of oxidative catalysts important in the biosynthesis and metabolism of a wide range of endogenous molecules as well as the metabolism of xenobiotics. For example, CYP2B4 metabolises substituted amines, CYP2E1 metabolises various alcohols and halogenated alkenes, and CYP1A2 catalyzes the oxygenation of aromatic compounds and polycyclic hydrocarbons. 4-phenyl-1,2,3-Thiadiazole is, at 100 µM, a selective inhibitor of certain CYP450 enzymes (CYP2B4, CYP2E1), but not others (CYP1A2), with inactivation occurring in a mechanism-based manner.

Supplier: Cayman Chemical

3,3',5,5'-Tetramethylbenzidine dihydrochloride hydrate

Supplier: Cayman Chemical

5,5'-Dithiobis(2-nitrobenzoic acid) (Ellmans reagent, DTNB)

Supplier: Cayman Chemical

Baicalein