Membrane potential detection kit, MITO-ID®

MITO-ID® membrane potential detection kit monitors energetic status using a simple mix-and-read, no-wash protocol. It measures mitochondrial membrane potential with a cationic dye that fluoresces either green or orange depending upon membrane potential status.

• Highly sensitive detection of mitochondrial membrane potential decline
• Aids in the drug research process in preclinical drug safety assessment (ADME-Tox)
• Suitable for chemical/environmental toxicity screening and characterisation
• True mix-and-read homogeneous assay for live cells
• Optimized for the measurement of mitochondria membrane potential (MMP) and cell viability by fluorescence microscopy and flow cytometry

Cell-based assays for evaluating the functional status of mitochondria are useful tools for elucidating the role of mitochondrial activity in drug-induced toxicity, the apoptosis cascade and other cellular and biochemical processes.

Delivery information: Kit contains MITO-ID® MP detection reagent, necrosis detection reagent, CCCP control, 10X assay buffer 1 and 50X assay buffer 2.