SecinH3 is a selective inhibitor of cytohesins, blocking human, mouse, and Drosophila cytohesins with IC50 values of 2.4 to 5.6 µM.{ 14565} It binds the Sec7 domain of these small Arf-GEFs but does not bind Sec7 domains of larger Arf-GEFs.{25739} In 1 * 5 mg
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