- Antibody type:Primary
- Antigen name:integrin alpha X
- Antigen symbol:Itgax
- Clonality:Monoclonal
- Clone:N418
- Conjugation:Biotin
- Flow cytometry:Yes
- Host:Hamster
- Isotype:IgG
- Reactivity:Mouse
- Cross adsorption:No
- Form:liquid
- Gene ID:Q9QXH4
- Antigen synonyms:Itgax
- Storage buffer:Phosphate-buffered aqueous solution, ≤0,09% Sodium azide, may contain carrier protein/stabiliser, ph 7,2.
- Storage temperature:The product should be stored undiluted at 4 °C and should be protected from prolonged exposure to light. Do not freeze.
- Shipping temperature:4 °C
- Purification:The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
- Pk:0,5 mg
The N418 monoclonal antibody specifically reacts with the integrin alpha x chain of the mouse CD11c, which is expressed on dendritic cells, CD4-/CD8+ intestinal intraepithelial lymphocytes (IEL) and some activated T lymphocytes. Low levels of CD11c were detected on mouse splenic natural killer cells and on the monocyte/macrophage lineage cells.CD11c expression is upregulated on IEL and T lymphocytes after activation. It binds to CD54, fibrinogen and iC3b and influences the leukocyte adhesive interactions. The N418 antibody binds to CD11c on splenic dendritic cells of the mouse in the T-dependent areas. It also contributes to the binding of iC3b.
Type: Primary
Antigen: Itgax
Clonality: Monoclonal
Clone: N418
Conjugation: Biotin
Epitope:
Host: Hamster
Isotype: IgG
Reactivity: Mouse