- Antibody type:Primary
- Antigen name:RNF98
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Environmentally Preferable:
- Epitope:201-300/728
- Form:Liquid
- Gene ID:55521
- Antigen synonyms:TRI36_HUMAN|E3 ubiquitin protein ligase TRIM36|Acrosome RBCC protein|Zinc-binding protein Rbcc728|Haprin|TRIM36|Tripartite mot-containing protein 36|Tripartite mot containing 36|Ring finger protein 98|E3 ubiquitin-protein ligase Trim36|TRIM 36|RBCC728|Tripartite mot protein 36|Tripartite mot containing protein 36|Zinc binding protein Rbcc728
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Storage temperature:Store at ‒20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human TRIM36/RNF98
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
TRIM36 (tripartite motif-containing 36), also known as RNF98 (RING finger protein 98), HAPRIN (haploid germ cell-specific RBCC protein) or RBCC728, is a 728 amino acid protein that belongs to the TRIM/RBCC (Ring finger, B box, coiled-coil) family. Predominantly expressed in prostate, testis and brain with weak expression in heart, kidney and lung, TRIM36 contains two B box-type zinc fingers, a SPRY domain, a coiled-coil domain, a fibronectin type-III domain and a RING-type zinc finger; a motif that has zinc-chelating activity and is involved in mediating protein-protein and protein-DNA interactions. Localising to the cytoplasm and the acrosomal region of germ cells and mature sperm, TRIM36 is believed to play a role in the acrosome reaction and fertilisation. In addition, TRIM36 is overexpressed in prostate cancer, suggesting a possible role for TRIM36 in prostate tumorigenesis.
Type: Primary
Antigen: RNF98
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 201-300/728
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse; Rat