Specifications
- Antibody type:Primary
- Antigen name:Adenovirus 5 E1A
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Virus,Rat
- Western blot:Yes
- Epitope:181-280/289
- Form:Liquid
- Antigen synonyms:E1A_ADE05|Human adenovirus C|Control protein E1A|Human adenovirus type 5|Adenovirus early E1A protein|E1A|pfam02703|Early E1A protein
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:32 kDa
- Storage temperature:Store at ‒20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human Adenovirus 5 E1A
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
The early region (E1) of the adenovirus genome, responsible for transforming activity, is localised within the left most 11% of the viral genome and consists of two transcriptional units E1A and E1B. E1A is sufficient for partial transformation and immortalisation of primary cells. E1A gene products are necessary for normal levels of transcription of the other early regions of the adenovirus genome during productive infection and are able to either activate or repress the transcription of specific cellular genes. E1A forms specific complexes with cellular proteins including p105 causing inhibition of the cell cycle inducing arresting function of p105.
Type: Primary
Antigen: Adenovirus 5 E1A
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 181-280/289
Host: Rabbit
Isotype: IgG
Reactivity: Rat; Virus